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A Novel, Orally Bioavailable, Small-Molecule Inhibitor of PCSK9 With Significant Cholesterol-Lowering Properties In Vivo.
Suchowerska, Alexandra K; Stokman, Geurt; Palmer, James T; Coghlan, Phillip A; Pieterman, Elsbet J; Keijzer, Nanda; Lambert, Gilles; Chemello, Kevin; Jaafar, Ali K; Parmar, Jasneet; Yan, Liping; Tong, Yingtao; Mu, Lin; Princen, Hans M G; Bonnar, James; Evison, Benny J.
Afiliación
  • Suchowerska AK; Nyrada Inc., Gordon, New South Wales, Australia.
  • Stokman G; Metabolic Health Research, The Netherlands Organization of Applied Scientific Research, Leiden, The Netherlands.
  • Palmer JT; Pharmaceutical Discovery Consultation, Warrandyte, Victoria, Australia.
  • Coghlan PA; i-Chem Consulting, Condell Park, New South Wales, Australia.
  • Pieterman EJ; Metabolic Health Research, The Netherlands Organization of Applied Scientific Research, Leiden, The Netherlands.
  • Keijzer N; Metabolic Health Research, The Netherlands Organization of Applied Scientific Research, Leiden, The Netherlands.
  • Lambert G; Laboratoire Inserm UMR 1188 DeTROI, Universite de la Reunion Plateforme CYROI, Sainte Clotilde, France.
  • Chemello K; Laboratoire Inserm UMR 1188 DeTROI, Universite de la Reunion Plateforme CYROI, Sainte Clotilde, France.
  • Jaafar AK; Laboratoire Inserm UMR 1188 DeTROI, Universite de la Reunion Plateforme CYROI, Sainte Clotilde, France.
  • Parmar J; Nyrada Inc., Gordon, New South Wales, Australia.
  • Yan L; DMPK/Exploratory Toxicology Department, Shanghai ChemPartner Co., Ltd., Shanghai, China.
  • Tong Y; DMPK/Exploratory Toxicology Department, Shanghai ChemPartner Co., Ltd., Shanghai, China.
  • Mu L; DMPK/Exploratory Toxicology Department, Shanghai ChemPartner Co., Ltd., Shanghai, China.
  • Princen HMG; Metabolic Health Research, The Netherlands Organization of Applied Scientific Research, Leiden, The Netherlands.
  • Bonnar J; Nyrada Inc., Gordon, New South Wales, Australia.
  • Evison BJ; Nyrada Inc., Gordon, New South Wales, Australia. Electronic address: benny.evison@nyrada.com.
J Lipid Res ; 63(11): 100293, 2022 11.
Article en En | MEDLINE | ID: mdl-36209894
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de LDL / Inhibidores de PCSK9 / Hiperlipidemias / Anticolesterolemiantes Límite: Animals / Humans Idioma: En Revista: J Lipid Res Año: 2022 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de LDL / Inhibidores de PCSK9 / Hiperlipidemias / Anticolesterolemiantes Límite: Animals / Humans Idioma: En Revista: J Lipid Res Año: 2022 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos