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The Copenhagen Actinic Keratosis Study (COAKS). A decentralised clinical trial to evaluate tolerability, safety and efficacy of daily field-directed topical treatment with cytosolic phospholipase A2 inhibitor, AVX001, in participants with actinic keratosis: protocol for a randomised controlled phase I/IIa trial.
Ortner, Vinzent Kevin; Johansen, Berit; Kilov, Kim; Castillo Mondragón, Alejandro; Duvold, Tore; Kihl, Jesper; Ashcroft, Felicity J; Feuerherm, Astrid J; Pind Laugesen, Charlotte; Marcker Espersen, Maiken Lise; Manole, Ionela; Isberg, Ari Pall; Andersen, Anders Daniel; Rakvaag, Elin; Zibert, John R; Haedersdal, Merete.
Afiliación
  • Ortner VK; Department of Dermatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, 2400 Copenhagen, Denmark vinzent.kevin.ortner@regionh.dk.
  • Johansen B; Clinical Operations, Coegin Pharma AB, Lund, Sweden.
  • Kilov K; Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway.
  • Castillo Mondragón A; Studies&Me, Copenhagen, Denmark.
  • Duvold T; Studies&Me, Copenhagen, Denmark.
  • Kihl J; Clinical Operations, Coegin Pharma AB, Lund, Sweden.
  • Ashcroft FJ; Clinical Operations, Coegin Pharma AB, Lund, Sweden.
  • Feuerherm AJ; Clinical Operations, Coegin Pharma AB, Lund, Sweden.
  • Pind Laugesen C; Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway.
  • Marcker Espersen ML; Clinical Operations, Coegin Pharma AB, Lund, Sweden.
  • Manole I; Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway.
  • Isberg AP; Studies&Me, Copenhagen, Denmark.
  • Andersen AD; Studies&Me, Copenhagen, Denmark.
  • Rakvaag E; Second Department of Dermatology, Colentina Clinical Hospital, Bucharest, Romania.
  • Zibert JR; Studies&Me, Copenhagen, Denmark.
  • Haedersdal M; Studies&Me, Copenhagen, Denmark.
BMJ Open ; 12(10): e061012, 2022 10 05.
Article en En | MEDLINE | ID: mdl-36198452
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácidos Grasos Omega-3 / Queratosis Actínica / Inhibidores de Fosfolipasa A2 Tipo de estudio: Clinical_trials / Guideline Aspecto: Ethics Límite: Adult / Humans Idioma: En Revista: BMJ Open Año: 2022 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácidos Grasos Omega-3 / Queratosis Actínica / Inhibidores de Fosfolipasa A2 Tipo de estudio: Clinical_trials / Guideline Aspecto: Ethics Límite: Adult / Humans Idioma: En Revista: BMJ Open Año: 2022 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido