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Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress.
Shrestha, Shristi; Erikson, Galina; Lyon, James; Spigelman, Aliya F; Bautista, Austin; Manning Fox, Jocelyn E; Dos Santos, Cristiane; Shokhirev, Maxim; Cartailler, Jean-Philippe; Hetzer, Martin W; MacDonald, Patrick E; Arrojo E Drigo, Rafael.
Afiliación
  • Shrestha S; Creative Data Solutions, Vanderbilt Center for Stem Cell Biology, Nashville, TN 37232, USA.
  • Erikson G; Integrative Genomics and Bioinformatics Core, Salk Institute of Biological Studies, La Jolla, CA 92037, USA.
  • Lyon J; Department of Pharmacology and Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta T6G2E1, Canada.
  • Spigelman AF; Department of Pharmacology and Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta T6G2E1, Canada.
  • Bautista A; Department of Pharmacology and Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta T6G2E1, Canada.
  • Manning Fox JE; Department of Pharmacology and Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta T6G2E1, Canada.
  • Dos Santos C; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA.
  • Shokhirev M; Integrative Genomics and Bioinformatics Core, Salk Institute of Biological Studies, La Jolla, CA 92037, USA.
  • Cartailler JP; Creative Data Solutions, Vanderbilt Center for Stem Cell Biology, Nashville, TN 37232, USA.
  • Hetzer MW; Molecular and Cell Biology Laboratory, Salk Institute of Biological Studies, La Jolla, CA 92037, USA.
  • MacDonald PE; Department of Pharmacology and Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta T6G2E1, Canada.
  • Arrojo E Drigo R; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA.
Sci Adv ; 8(40): eabo3932, 2022 Oct 07.
Article en En | MEDLINE | ID: mdl-36197983

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Sci Adv Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Sci Adv Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos