Quinonoid dihydropteridine reductase, a tetrahydrobiopterin-recycling enzyme, contributes to 5-hydroxytryptamine-associated platelet aggregation in mice.

Suganuma, Yui; Sumi-Ichinose, Chiho; Kano, Taiki; Ikemoto, Kazuhisa; Matsui, Taei; Ichinose, Hiroshi; Kondo, Kazunao

Suganuma, Yui; Sumi-Ichinose, Chiho; Kano, Taiki; Ikemoto, Kazuhisa; Matsui, Taei; Ichinose, Hiroshi; Kondo, Kazunao.

Afiliación

Suganuma Y; Department of Pharmacology, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan.
Sumi-Ichinose C; Department of Pharmacology, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan.
Kano T; Department of Pharmacology, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan.
Ikemoto K; Department of Pharmacology, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan.
Matsui T; Department of Biology, School of Medical Sciences, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan.
Ichinose H; School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan.
Kondo K; Department of Pharmacology, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan. Electronic address: k17kondo@fujita-hu.ac.jp.

J Pharmacol Sci ; 150(3): 173-179, 2022 Nov.

Article en En | MEDLINE | ID: mdl-36184122

Asunto(s)

Dihidropteridina Reductasa; Agregación Plaquetaria; 5-Hidroxitriptófano/farmacología; Adenosina Difosfato/farmacología; Animales; Biopterinas/análogos & derivados; Catecolaminas; Colágeno; Dihidropteridina Reductasa/genética; Dihidropteridina Reductasa/farmacología; Ratones; Receptor de Serotonina 5-HT2A; Serotonina/farmacología

Palabras clave

Platelet aggregation; Quinonoid dihydropteridine reductase; Secondary aggregation; Serotonin; Tetrahydrobiopterin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Agregación Plaquetaria / Dihidropteridina Reductasa Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: J Pharmacol Sci Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón

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