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Clozapine Reduces Recurrent Suicidal and Self-Injurious Behavior in Treatment-Refractory Incarcerated Individuals.
Zarzar, Theodore R; Rosen, David L; Mayo, James P; O'Connell, Maria G; Catlett, Terri L; Reed, John G; Williams, Joseph B; Sheitman, Brian B.
Afiliación
  • Zarzar TR; Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
  • Rosen DL; Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
  • Mayo JP; Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
  • O'Connell MG; North Carolina Department of Public Safety - Prisons, Raleigh, North Carolina, USA.
  • Catlett TL; North Carolina Department of Public Safety - Prisons, Raleigh, North Carolina, USA.
  • Reed JG; North Carolina Department of Public Safety - Prisons, Raleigh, North Carolina, USA.
  • Williams JB; Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
  • Sheitman BB; North Carolina Department of Public Safety - Prisons, Raleigh, North Carolina, USA.
J Correct Health Care ; 28(5): 329-335, 2022 10.
Article en En | MEDLINE | ID: mdl-36178970
This retrospective review examines clozapine's effects on treatment-refractory incarcerated individuals (N = 23) with recurrent thoughts of self-harm and/or self-injurious behavior. Emergent suicide risk assessments and days on suicide watch were assessed for the 3 months pre- and post-clozapine treatment. Total suicide assessments fell from 73 pre- to 14 post-clozapine, with a median of 2 assessments (interquartile range [IQR]: 1,5) pre-clozapine compared with 0 (IQR: 0,1) post-clozapine (p < 0.0001). Total days on suicide watch decreased from 104 days pre- to 32 post-clozapine, with a median of 3 days (IQR: 0,9) pre-clozapine compared with 0 (IQR: 0,0) post-clozapine (p = 0.0012). Emergency room visits and medical hospitalizations decreased substantially for all months of treatment. Clozapine treatment was associated with marked reductions in self-injurious thoughts and behaviors in high-risk incarcerated individuals.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Prisioneros / Suicidio / Conducta Autodestructiva / Clozapina Límite: Humans Idioma: En Revista: J Correct Health Care Asunto de la revista: SAUDE PUBLICA / SERVICOS DE SAUDE Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Prisioneros / Suicidio / Conducta Autodestructiva / Clozapina Límite: Humans Idioma: En Revista: J Correct Health Care Asunto de la revista: SAUDE PUBLICA / SERVICOS DE SAUDE Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos