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Progress towards the UNAIDS 90-90-90 targets among persons aged 50 and older living with HIV in 13 African countries.
Farley, Shannon M; Wang, Chunhui; Bray, Rachel M; Low, Andrea Jane; Delgado, Stephen; Hoos, David; Kakishozi, Angela N; Harris, Tiffany G; Nyirenda, Rose; Wadonda, Nellie; Li, Michelle; Amuri, Mbaraka; Juma, James; Kancheya, Nzali; Pietersen, Ismela; Mutenda, Nicholus; Natanael, Salomo; Aoko, Appolonia; Ngugi, Evelyn W; Asiimwe, Fred; Lecher, Shirley; Ward, Jennifer; Chikwanda, Prisca; Mugurungi, Owen; Moyo, Brian; Nkurunziza, Peter; Aibo, Dorothy; Kabala, Andrew; Biraro, Sam; Ndagije, Felix; Musuka, Godfrey; Ndongmo, Clement; Shang, Judith; Dokubo, Emily K; Dimite, Laura E; McCullough-Sanden, Rachel; Bissek, Anne-Cecile; Getaneh, Yimam; Eshetu, Frehywot; Nkumbula, Tepa; Tenthani, Lyson; Kayigamba, Felix R; Kirungi, Wilford; Musinguzi, Joshua; Balachandra, Shirish; Kayirangwa, Eugenie; Ayite, Ayiyi; West, Christine A; Bodika, Stephane; Sleeman, Katrina.
Afiliación
  • Farley SM; ICAP at Columbia University, New York City, New York, USA.
  • Wang C; ICAP at Columbia University, New York City, New York, USA.
  • Bray RM; ICAP at Columbia University, New York City, New York, USA.
  • Low AJ; ICAP at Columbia University, New York City, New York, USA.
  • Delgado S; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, New York, USA.
  • Hoos D; ICAP at Columbia University, New York City, New York, USA.
  • Kakishozi AN; ICAP at Columbia University, New York City, New York, USA.
  • Harris TG; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, New York, USA.
  • Nyirenda R; ICAP at Columbia University, New York City, New York, USA.
  • Wadonda N; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, New York, USA.
  • Li M; Malawi Ministry of Health, Lilongwe, Malawi.
  • Amuri M; US Centers for Disease Control and Prevention (CDC), Lilongwe, Malawi.
  • Juma J; CDC, Mbabane, Eswatini.
  • Kancheya N; CDC, Dar es Salaam, Tanzania.
  • Pietersen I; Ministry of Health, Community Development, Gender, Elderly and Children through The National AIDS Control Program (NACP), Dodoma, Tanzania.
  • Mutenda N; CDC, Lusaka, Zambia.
  • Natanael S; CDC, Windhoek, Namibia.
  • Aoko A; Ministry of Health and Social Services, Windhoek, Namibia.
  • Ngugi EW; Ministry of Health and Social Services, Windhoek, Namibia.
  • Asiimwe F; CDC, Nairobi, Kenya.
  • Lecher S; CDC, Nairobi, Kenya.
  • Ward J; CDC, Maseru, Lesotho.
  • Chikwanda P; CDC, Maseru, Lesotho.
  • Mugurungi O; CDC, Kampala, Uganda.
  • Moyo B; CDC, Harare, Zimbabwe.
  • Nkurunziza P; Zimbabwe Ministry of Health and Child Care, Hararre, Zimbabwe.
  • Aibo D; Zimbabwe Ministry of Health and Child Care, Hararre, Zimbabwe.
  • Kabala A; ICAP at Columbia University, New York City, New York, USA.
  • Biraro S; ICAP at Columbia University, New York City, New York, USA.
  • Ndagije F; ICAP at Columbia University, New York City, New York, USA.
  • Musuka G; ICAP at Columbia University, New York City, New York, USA.
  • Ndongmo C; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, New York, USA.
  • Shang J; ICAP at Columbia University, New York City, New York, USA.
  • Dokubo EK; ICAP at Columbia University, New York City, New York, USA.
  • Dimite LE; CDC, Yaounde, Cameroon.
  • McCullough-Sanden R; CDC, Yaounde, Cameroon.
  • Bissek AC; CDC, Yaounde, Cameroon.
  • Getaneh Y; CDC, Yaounde, Cameroon.
  • Eshetu F; CDC, Yaounde, Cameroon.
  • Nkumbula T; Cameroon Ministry of Public Health, Yaounde, Cameroon.
  • Tenthani L; Ethiopia Public Health Institute, Addis Ababa, Ethiopia.
  • Kayigamba FR; CDC, Addis Ababa, Ethiopia.
  • Kirungi W; ICAP at Columbia University, New York City, New York, USA.
  • Musinguzi J; ICAP at Columbia University, New York City, New York, USA.
  • Balachandra S; ICAP at Columbia University, New York City, New York, USA.
  • Kayirangwa E; Uganda Ministry of Health, Kampala, Uganda.
  • Ayite A; Uganda Ministry of Health, Kampala, Uganda.
  • West CA; CDC, Abidjan, Cote d'Ivoire.
  • Bodika S; CDC, Kigali, Rwanda.
  • Sleeman K; CDC, Atlanta, Georgia, USA.
J Int AIDS Soc ; 25 Suppl 4: e26005, 2022 09.
Article en En | MEDLINE | ID: mdl-36176030
INTRODUCTION: Achieving optimal HIV outcomes, as measured by global 90-90-90 targets, that is awareness of HIV-positive status, receipt of antiretroviral (ARV) therapy among aware and viral load (VL) suppression among those on ARVs, respectively, is critical. However, few data from sub-Saharan Africa (SSA) are available on older people (50+) living with HIV (OPLWH). We examined 90-90-90 progress by age, 15-49 (as a comparison) and 50+ years, with further analyses among 50+ (55-59, 60-64, 65+ vs. 50-54), in 13 countries (Cameroon, Cote d'Ivoire, Eswatini, Ethiopia, Kenya, Lesotho, Malawi, Namibia, Rwanda, Tanzania, Uganda, Zambia and Zimbabwe). METHODS: Using data from nationally representative Population-based HIV Impact Assessments, conducted between 2015and 2019, participants from randomly selected households provided demographic and clinical information and whole blood specimens for HIV serology, VL and ARV testing. Survey weighted outcomes were estimated for 90-90-90 targets. Country-specific Poisson regression models examined 90-90-90 variation among OPLWH age strata. RESULTS: Analyses included 24,826 HIV-positive individuals (15-49 years: 20,170; 50+ years: 4656). The first, second and third 90 outcomes were achieved in 1, 10 and 5 countries, respectively, by those aged 15-49, while OPLWH achieved outcomes in 3, 13 and 12 countries, respectively. Among those aged 15-49, women were more likely to achieve 90-90-90 targets than men; however, among OPLWH, men were more likely to achieve first and third 90 targets than women, with second 90 achievement being equivalent. Country-specific 90-90-90 regression models among OPLWH demonstrated minimal variation by age stratum across 13 countries. Among OLPWH, no first 90 target differences were noted by age strata; three countries varied in the second 90 by older age strata but not in a consistent direction; one country showed higher achievement of the third 90 in an older age stratum. CONCLUSIONS: While OPLWH in these 13 countries were slightly more likely than younger people to be aware of their HIV-positive status (first 90), this target was not achieved in most countries. However, OPLWH achieved treatment (second 90) and VL suppression (third 90) targets in more countries than PLWH <50. Findings support expanded HIV testing, prevention and treatment services to meet ongoing OPLWH health needs in SSA.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: J Int AIDS Soc Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: J Int AIDS Soc Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza