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Factors associated with artificial airway retention after skull base chordoma resection: A retrospective cohort study.
Fu, Yuxuan; Yu, Yun; Cui, Yidan; Wang, Jing; Ma, Bo; Jian, Minyu; Yao, Jingxin; Jing, Longnian; Bai, Jiwei; Han, Ruquan.
Afiliación
  • Fu Y; Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Yu Y; Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Cui Y; Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Wang J; Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Ma B; Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Jian M; Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Yao J; Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Jing L; Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Bai J; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Han R; Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Front Neurol ; 13: 992308, 2022.
Article en En | MEDLINE | ID: mdl-36158950
Background: Chordoma is a malignant bone and soft tissue tumor derived from embryonic notochord remnants, and skull base chordoma accounts for ~1/3 of all chordoma cases. Skull base chordoma is closely related to the brainstem and cranial nerves and has a high recurrence rate. The purpose of this study was to investigate the influence of the timing of tracheal extubation on perioperative pulmonary complications. We also aimed to explore predictors of postoperative artificial airway (AA) retention in patients with skull base chordoma. Methods: This was a single-center, retrospective cohort study. The study population included all skull base chordoma patients undergoing surgical treatment between January 2019 and December 2021 at Beijing Tiantan Hospital. The primary outcome was the incidence of postoperative pulmonary complications. Several patient characteristics were evaluated for potential associations with AA retention. Results: A total of 310 patients with skull base chordoma were enrolled. The frequency of AA retention after surgery for skull base chordoma was 30.97%. The incidence of postoperative pulmonary complications was much lower in those without AA retention (3.74 vs. 39.58%, P < 0.001). Factors with the highest point estimates for the odds of AA retention included body mass index, cranial nerve involvement, maximum tumor diameter, operative method, hemorrhage volume, operative duration and intraoperative mechanical ventilation duration. Conclusions: In this retrospective cohort study, most of the factors associated with postoperative airway retention were closely related to the patient's tumor characteristics. These data demonstrate that respiratory management in patients with skull base chordoma remains an ongoing concern.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Neurol Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Neurol Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza