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The association of high-fluoride and high-iodine combined exposure with dental fluorosis and goiter: a meta-analysis.
Mou, Yahao; Qu, Tengjiao; Wang, Ruiyu; Zhang, Yulu; He, Zuoshun; Gu, Shiyan.
Afiliación
  • Mou Y; Department of Environmental and Occupational Health, Faculty of Public Health, Dali University, Dali, Yunnan, China.
  • Qu T; Department of Environmental and Occupational Health, Faculty of Public Health, Dali University, Dali, Yunnan, China.
  • Wang R; Department of Environmental and Occupational Health, Faculty of Public Health, Dali University, Dali, Yunnan, China.
  • Zhang Y; Department of Environmental and Occupational Health, Faculty of Public Health, Dali University, Dali, Yunnan, China.
  • He Z; Department of Environmental and Occupational Health, Faculty of Public Health, Dali University, Dali, Yunnan, China.
  • Gu S; Department of Environmental and Occupational Health, Faculty of Public Health, Dali University, Dali, Yunnan, China. ygsy727@163.com.
Environ Geochem Health ; 45(6): 3143-3153, 2023 Jun.
Article en En | MEDLINE | ID: mdl-36155875
It is controversial that high-fluoride and high-iodine combined exposure affects the prevalence of dental fluorosis and goiter. The aim of this study was to explore the potential association between high-fluoride and high-iodine combined exposure with dental fluorosis and goiter. We retrieved relevant articles from PubMed, Cochrane Library, China National Knowledge Infrastructure, Wanfang Database and China Science and Technology Journal Database (VIP). The query format was 1 # "Fluorosis" OR "Fluoride," 2 # "Iodine" OR "Iodide," and 3 # 1 AND 2. A total of 20 papers were included in this study after independent review by two investigators. Our analysis showed that high-fluoride and high-iodine biphasic exposure was significantly associated with the prevalence of goiter (OR = 4.69, 95% CI 2.82-7.80, P < 0.001). The prevalence of dental fluorosis was also significantly raised (OR = 11.71, 95% CI 7.57-18.14, P < 0.001). Sensitivity analysis suggested that combined statistics of multiple studies were reliable. For goiter, subgroup analysis revealed study province, sample size and published year as sources of heterogeneity (P < 0.001). For dental fluorosis, only sample size was the impact factor of heterogeneity. As well, funnel plot, Begg's test and Egger's test suggested there was no publication bias (P > 0.05). Overall, our study demonstrates that high-fluoride and high-iodine combined exposure is a risk factor for occurrence of dental fluorosis and goiter. The chronic of high-fluoride and high-iodine combined exposure is a significant higher risk of disease than normal.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bocio / Yodo / Fluorosis Dental Tipo de estudio: Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Environ Geochem Health Asunto de la revista: QUIMICA / SAUDE AMBIENTAL Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bocio / Yodo / Fluorosis Dental Tipo de estudio: Risk_factors_studies / Systematic_reviews Límite: Humans Idioma: En Revista: Environ Geochem Health Asunto de la revista: QUIMICA / SAUDE AMBIENTAL Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos