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Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR3.
Kinoshita, Seisho; Nakakido, Makoto; Mori, Chinatsu; Kuroda, Daisuke; Caaveiro, Jose M M; Tsumoto, Kouhei.
Afiliación
  • Kinoshita S; Department of Bioengineering, School of Engineering, The University of Tokyo, Tokyo, Japan.
  • Nakakido M; Department of Bioengineering, School of Engineering, The University of Tokyo, Tokyo, Japan.
  • Mori C; Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan.
  • Kuroda D; Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan.
  • Caaveiro JMM; Department of Bioengineering, School of Engineering, The University of Tokyo, Tokyo, Japan.
  • Tsumoto K; Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan.
Protein Sci ; 31(11): e4450, 2022 11.
Article en En | MEDLINE | ID: mdl-36153698

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regiones Determinantes de Complementariedad / Anticuerpos de Dominio Único Idioma: En Revista: Protein Sci Asunto de la revista: BIOQUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regiones Determinantes de Complementariedad / Anticuerpos de Dominio Único Idioma: En Revista: Protein Sci Asunto de la revista: BIOQUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos