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Long-term pituitary down-regulation pretreatment for endometriosis - chronicles of guidelines and recommendations.
Michaeli, Jennia; Dior, Uri P; Fainaru, Ofer; Revel, Ariel.
Afiliación
  • Michaeli J; Mount Sinai Fertility, Sinai Health System, Toronto, Ontario, Canada; Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada. Electronic address: jennia.michaeli@gmail.com.
  • Dior UP; Endometriosis Center, Hadassah Ein-Kerem Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
  • Fainaru O; IVF Unit, Rambam Health Care Campus, and Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
  • Revel A; Reproductive Medicine and In Vitro Fertilization Unit, Department of Obstetrics and Gynecology, Yitzhak Shamir Medical Center (formerly Assaf Harofeh Medical Center), Zerifin, Israel, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Reprod Biomed Online ; 45(5): 843-846, 2022 11.
Article en En | MEDLINE | ID: mdl-36151012
It was suggested in the 1980s that long-term pituitary down-regulation by a gonadotrophin-releasing hormone agonist, termed the ultra-long protocol, inducing a hypo-oestrogenic state, might improve reproductive outcomes in women with endometriosis. Subsequently, international guidelines strongly supported the long-term pituitary down-regulation protocol in women with endometriosis based on a Cochrane review from 2006. The recently published European Society for Human Reproduction and Embryology guideline, based on the updated Cochrane review from 2019 and newer evidence, has reversed this recommendation. This paper explores the past and current evidence that led to these recommendations and calls for a consideration of refinement of the international guidelines to include additional factors and evaluate whether a paradigm shift is needed in the approach to endometriosis-related infertility. We believe that this can optimize evidence-based patient-centred care and benefit women worldwide and improve the design of future studies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Endometriosis Tipo de estudio: Guideline Límite: Female / Humans Idioma: En Revista: Reprod Biomed Online Asunto de la revista: MEDICINA REPRODUTIVA Año: 2022 Tipo del documento: Article Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Endometriosis Tipo de estudio: Guideline Límite: Female / Humans Idioma: En Revista: Reprod Biomed Online Asunto de la revista: MEDICINA REPRODUTIVA Año: 2022 Tipo del documento: Article Pais de publicación: Países Bajos