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Associations between presence of diabetes, mortality and fracture type in individuals with a hip fracture.
Spaetgens, Bart; Brouns, Steffie H A; Linkens, Aimée E M J H; Poeze, Martijn; Ten Broeke, René H M; Brüggemann, Renée A G; Sipers, Walther; Henry, Ronald M A; Hanssen, Nordin M J.
Afiliación
  • Spaetgens B; Department of Internal Medicine, Division of General Internal Medicine, Section Geriatric Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands. Electronic address: Barthol
  • Brouns SHA; Department of Internal Medicine, Division of General Internal Medicine, Section Geriatric Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.
  • Linkens AEMJH; Department of Internal Medicine, Division of General Internal Medicine, Section Geriatric Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.
  • Poeze M; Department of Trauma Surgery, Maastricht University Medical Centre, Maastricht, the Netherlands.
  • Ten Broeke RHM; Department of Orthopedic Surgery, Maastricht University Medical Centre, Maastricht, the Netherlands.
  • Brüggemann RAG; Department of Internal Medicine, Division of General Internal Medicine, Section Geriatric Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.
  • Sipers W; Department of Geriatric Medicine, Zuyderland Medical Centre, Sittard-Geleen, the Netherlands.
  • Henry RMA; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands; Department of Internal Medicine, Division of General Internal Medicine, Section Acute Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.
  • Hanssen NMJ; Amsterdam Diabetes Centre, Department of Internal and Vascular Medicine, Amsterdam UMC, Location AMC, Amsterdam, the Netherlands.
Diabetes Res Clin Pract ; 192: 110084, 2022 Oct.
Article en En | MEDLINE | ID: mdl-36122868
AIMS: An overlooked aspect of diabetes is an increased risk of hip fractures, with associated mortality. We investigated whether fracture type and/or burden of comorbidities explains the increased risk of mortality in diabetes after hip fracture. METHODS: For this cohort study, we used a de-identified data set of hip fracture patients registered in a quality-of-care registry (2017/2018) included in Maastricht University Medical Centre. RESULTS: Among 594 hip fracture patients, 90 (15.2 %) had diabetes. Median (IQR) age was 82 (71-87) years and 63.8 % were women. Compared to patients without, patients with diabetes had higher median Charlson Comorbidity Index [1 (0-2) vs 0 (0-2), P < 0.001)] and were more likely to sustain intertrochanteric/subtrochanteric fractures [54.4 vs 38.7 %, P = 0.02]. Over a median follow-up of 2.7 (1.6-3.3) years, crude mortality rate was 30.8 % in patients without and 50.0 % in patients with diabetes. This association remained unaltered after adjustment for age, sex, BMI, fracture type or burden of co-morbidities. CONCLUSION: Individuals with diabetes display a greatly increased absolute mortality risk after hip fracture. This association was not attenuated after adjustment for fracture type or non-diabetes associated co-morbidity. These findings have important implications for diabetes care in hip fracture patients, and underline the importance of fracture prevention.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus / Fracturas de Cadera Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged80 / Female / Humans / Male Idioma: En Revista: Diabetes Res Clin Pract Asunto de la revista: ENDOCRINOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Irlanda
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus / Fracturas de Cadera Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged80 / Female / Humans / Male Idioma: En Revista: Diabetes Res Clin Pract Asunto de la revista: ENDOCRINOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Irlanda