Construction and characterization of a contagious ecthyma virus double-gene deletion strain and evaluation of its potential as a live-attenuated vaccine in goat.

Zhu, Zhen; Qu, Guanggang; Du, Jige; Wang, Changjiang; Chen, Yong; Shen, Zhanning; Zhou, Zhiyu; Yin, Chunsheng; Chen, Xiaoyun

Zhu, Zhen; Qu, Guanggang; Du, Jige; Wang, Changjiang; Chen, Yong; Shen, Zhanning; Zhou, Zhiyu; Yin, Chunsheng; Chen, Xiaoyun.

Afiliación

Zhu Z; China Institute of Veterinary Drug Control, Beijing, China.
Qu G; Shandong Binzhou Animal Science and Veterinary Medicine Academy, Binzhou, China.
Du J; China Institute of Veterinary Drug Control, Beijing, China.
Wang C; Shandong Binzhou Animal Science and Veterinary Medicine Academy, Binzhou, China.
Chen Y; China Institute of Veterinary Drug Control, Beijing, China.
Shen Z; China Institute of Veterinary Drug Control, Beijing, China.
Zhou Z; China Institute of Veterinary Drug Control, Beijing, China.
Yin C; China Institute of Veterinary Drug Control, Beijing, China.
Chen X; China Institute of Veterinary Drug Control, Beijing, China.

Front Immunol ; 13: 961287, 2022.

Article en En | MEDLINE | ID: mdl-36119021

Asunto(s)

Ectima Contagioso; Virus del Orf; Animales; Ectima Contagioso/genética; Ectima Contagioso/patología; Eliminación de Gen; Cabras; Humanos; Factor Estimulante de Colonias de Macrófagos/genética; Masculino; Virus del Orf/genética; Ovinos; Oveja Doméstica; Vacunas Atenuadas

Palabras clave

ORFV; cbp; double gene deletion; gif; protection efficacy; recombinant virus; safety; vaccine

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus del Orf / Ectima Contagioso Límite: Animals / Humans / Male Idioma: En Revista: Front Immunol Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

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