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Safety and efficacy of bulevirtide in combination with tenofovir disoproxil fumarate in patients with hepatitis B virus and hepatitis D virus coinfection (MYR202): a multicentre, randomised, parallel-group, open-label, phase 2 trial.
Wedemeyer, Heiner; Schöneweis, Katrin; Bogomolov, Pavel; Blank, Antje; Voronkova, Natalia; Stepanova, Tatiana; Sagalova, Olga; Chulanov, Vladimir; Osipenko, Marina; Morozov, Viacheslav; Geyvandova, Natalia; Sleptsova, Snezhana; Bakulin, Igor G; Khaertynova, Ilsiyar; Rusanova, Marina; Pathil, Anita; Merle, Uta; Bremer, Birgit; Allweiss, Lena; Lempp, Florian A; Port, Kerstin; Haag, Mathias; Schwab, Matthias; Zur Wiesch, Julian Schulze; Cornberg, Markus; Haefeli, Walter E; Dandri, Maura; Alexandrov, Alexander; Urban, Stephan.
Afiliación
  • Wedemeyer H; Department of Gastroenterology, Hepatology, and Endocrinology, Cluster of Excellence RESIST (EXC 2155), Hannover, Germany; Hannover Medical School, Hannover, Germany; German Center for Infection Research (DZIF) partner site, Hannover-Braunschweig, Braunschweig, Germany. Electronic address: wedemeyer
  • Schöneweis K; MYR GmbH, Bad Homburg, Germany; Department of Infectious Diseases and Molecular Virology, Heidelberg University Hospital, Heidelberg, Germany.
  • Bogomolov P; Hepatology Department, Moscow Regional Scientific Research, Clinic Institute MF Vladimirsky, Moscow, Russia.
  • Blank A; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany; German Centre for Infection Research, Heidelberg, Germany.
  • Voronkova N; H-Clinic, Moscow, Russia.
  • Stepanova T; Modern Medicine Clinic, Moscow, Russia.
  • Sagalova O; Clinic of the South-Ural State Medical University, Chelyabinsk, Russia.
  • Chulanov V; Reference Centre for Viral Hepatitis, Central Research Institute of Epidemiology, Moscow, Russia.
  • Osipenko M; Novosibirsk State Medical University, Novosibirsk, Russia.
  • Morozov V; Medical Company Hepatology, Samara, Russia.
  • Geyvandova N; Stavropol State Medical University, Stavropol Regional Clinical Hospital, Stavropol, Russia.
  • Sleptsova S; Department of Infectious Diseases, Physiology, Dermatology, and Venereology, Medical Institute of the North-Eastern Federal University MK Ammosov, Yakutsk, Russia.
  • Bakulin IG; Gastroenterology and Dietology SM Riss, North-Western State Medical University, Mechnikov, Russia.
  • Khaertynova I; Republican Clinical Infectious Diseases Hospital Professor AF Agafonov, Kazan, Russia.
  • Rusanova M; Infectious Clinical Hospital Number 1, Moscow City Department, Moscow, Russia.
  • Pathil A; Department of Internal Medicine I, Goethe University Hospital Frankfurt, Frankfurt, Germany.
  • Merle U; Internal Medicine IV Gastroenterology, Heidelberg University Hospital, Heidelberg, Germany.
  • Bremer B; Hannover Medical School, Hannover, Germany.
  • Allweiss L; University Hospital Hamburg-Eppendorf, Centre for Internal Medicine, Medical Clinic and Polyclinic, Hamburg, Germany; German Centre for Infection Research, Hamburg-Lübeck-Borstel-Riems, Germany.
  • Lempp FA; Department of Infectious Diseases and Molecular Virology, Heidelberg University Hospital, Heidelberg, Germany; German Centre for Infection Research, Heidelberg, Germany.
  • Port K; Hannover Medical School, Hannover, Germany.
  • Haag M; Clinical Pharmacology, Dr Margarete Fischer-Bosch-Institute, Stuttgart, Germany; University of Tuübingen, Tuübingen, Germany.
  • Schwab M; Clinical Pharmacology, Dr Margarete Fischer-Bosch-Institute, Stuttgart, Germany; Departments of Clinical Pharmacology, Biochemistry, and Pharmacy, University Hospital Tübingen, Tübingen, Germany.
  • Zur Wiesch JS; University Hospital Hamburg-Eppendorf, Centre for Internal Medicine, Medical Clinic and Polyclinic, Hamburg, Germany; German Centre for Infection Research, Hamburg-Lübeck-Borstel-Riems, Germany.
  • Cornberg M; Hannover Medical School, Hannover, Germany.
  • Haefeli WE; Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany; German Centre for Infection Research, Heidelberg, Germany.
  • Dandri M; University Hospital Hamburg-Eppendorf, Centre for Internal Medicine, Medical Clinic and Polyclinic, Hamburg, Germany; German Centre for Infection Research, Hamburg-Lübeck-Borstel-Riems, Germany.
  • Alexandrov A; MYR GmbH, Bad Homburg, Germany.
  • Urban S; Department of Infectious Diseases and Molecular Virology, Heidelberg University Hospital, Heidelberg, Germany; German Centre for Infection Research, Heidelberg, Germany. Electronic address: stephan.urban@med.uni-heidelberg.de.
Lancet Infect Dis ; 23(1): 117-129, 2023 01.
Article en En | MEDLINE | ID: mdl-36113537

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hepatitis D / Hepatitis B Crónica / Hepatitis D Crónica / Coinfección Tipo de estudio: Clinical_trials Límite: Adult / Humans Idioma: En Revista: Lancet Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hepatitis D / Hepatitis B Crónica / Hepatitis D Crónica / Coinfección Tipo de estudio: Clinical_trials Límite: Adult / Humans Idioma: En Revista: Lancet Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos