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De novo design and Rosetta-based assessment of high-affinity antibody variable regions (Fv) against the SARS-CoV-2 spike receptor binding domain (RBD).
Boorla, Veda Sheersh; Chowdhury, Ratul; Ramasubramanian, Ranjani; Ameglio, Brandon; Frick, Rahel; Gray, Jeffrey J; Maranas, Costas D.
Afiliación
  • Boorla VS; Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania, USA.
  • Chowdhury R; Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania, USA.
  • Ramasubramanian R; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
  • Ameglio B; Program in Molecular Biophysics, Johns Hopkins University, Baltimore, Maryland, USA.
  • Frick R; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
  • Gray JJ; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
  • Maranas CD; Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania, USA.
Proteins ; 91(2): 196-208, 2023 02.
Article en En | MEDLINE | ID: mdl-36111441
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Proteins Asunto de la revista: BIOQUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Proteins Asunto de la revista: BIOQUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos