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Homologous recombination-deficient mutation cluster in tumor suppressor RAD51C identified by comprehensive analysis of cancer variants.
Prakash, Rohit; Rawal, Yashpal; Sullivan, Meghan R; Grundy, McKenzie K; Bret, Hélène; Mihalevic, Michael J; Rein, Hayley L; Baird, Jared M; Darrah, Kristie; Zhang, Fang; Wang, Raymond; Traina, Tiffany A; Radke, Marc R; Kaufmann, Scott H; Swisher, Elizabeth M; Guérois, Raphaël; Modesti, Mauro; Sung, Patrick; Jasin, Maria; Bernstein, Kara A.
Afiliación
  • Prakash R; Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
  • Rawal Y; Department of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
  • Sullivan MR; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Grundy MK; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Bret H; Institute for Integrative Biology of the Cell, Université Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, 91198 France.
  • Mihalevic MJ; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Rein HL; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Baird JM; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Darrah K; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Zhang F; Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
  • Wang R; Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853.
  • Traina TA; Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
  • Radke MR; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
  • Kaufmann SH; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195.
  • Swisher EM; Departments of Oncology and Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905.
  • Guérois R; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA 98195.
  • Modesti M; Institute for Integrative Biology of the Cell, Université Paris-Saclay, CEA, CNRS, Gif-sur-Yvette, 91198 France.
  • Sung P; Cancer Research Center of Marseille, CNRS, INSERM, Institut Paoli-Calmettes, Aix-Marseille Université, Marseille, 13273 France.
  • Jasin M; Department of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
  • Bernstein KA; Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
Proc Natl Acad Sci U S A ; 119(38): e2202727119, 2022 09 20.
Article en En | MEDLINE | ID: mdl-36099300
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Proteínas Supresoras de Tumor / Proteínas de Unión al ADN / Recombinasa Rad51 / Recombinación Homóloga Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Proteínas Supresoras de Tumor / Proteínas de Unión al ADN / Recombinasa Rad51 / Recombinación Homóloga Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos