Application of physiologically-based pharmacokinetic/pharmacodynamic models to evaluate the interaction between nifedipine and apatinib.

Liu, Hongrui; Yu, Yiqun; Liu, Lu; Wang, Chunyan; Guo, Nan; Wang, Xiaojuan; Xiang, Xiaoqiang; Han, Bing

Liu, Hongrui; Yu, Yiqun; Liu, Lu; Wang, Chunyan; Guo, Nan; Wang, Xiaojuan; Xiang, Xiaoqiang; Han, Bing.

Afiliación

Liu H; Department of Pharmacy, Minhang Hospital, Fudan University, Shanghai, China.
Yu Y; Department of Pharmacy, Minhang Hospital, Fudan University, Shanghai, China.
Liu L; Department of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, China.
Wang C; Department of Pharmacy, Minhang Hospital, Fudan University, Shanghai, China.
Guo N; Department of Pharmacy, Minhang Hospital, Fudan University, Shanghai, China.
Wang X; Department of Pharmacy, Minhang Hospital, Fudan University, Shanghai, China.
Xiang X; Department of Pharmacy, Minhang Hospital, Fudan University, Shanghai, China.
Han B; Department of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, China.

Front Pharmacol ; 13: 970539, 2022.

Article en En | MEDLINE | ID: mdl-36091758

Palabras clave

apatinib; drug-drug interaction (DDI); nifedipine; pharmacodynamics; physiologically-based pharmacokinetics (PBPK)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

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