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The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer.
Mirji, Gauri; Worth, Alison; Bhat, Sajad Ahmad; El Sayed, Mohamed; Kannan, Toshitha; Goldman, Aaron R; Tang, Hsin-Yao; Liu, Qin; Auslander, Noam; Dang, Chi V; Abdel-Mohsen, Mohamed; Kossenkov, Andrew; Stanger, Ben Z; Shinde, Rahul S.
Afiliación
  • Mirji G; Immunology, Microenvironment and Metastasis Program, the Wistar Institute, Philadelphia, PA, USA.
  • Worth A; Immunology, Microenvironment and Metastasis Program, the Wistar Institute, Philadelphia, PA, USA.
  • Bhat SA; Immunology, Microenvironment and Metastasis Program, the Wistar Institute, Philadelphia, PA, USA.
  • El Sayed M; Immunology, Microenvironment and Metastasis Program, the Wistar Institute, Philadelphia, PA, USA.
  • Kannan T; Bioinformatics Facility, the Wistar Institute, Philadelphia, PA, USA.
  • Goldman AR; Proteomics and Metabolomics Facility, the Wistar Institute, Philadelphia, PA, USA.
  • Tang HY; Proteomics and Metabolomics Facility, the Wistar Institute, Philadelphia, PA, USA.
  • Liu Q; Molecular and Cellular Oncogenesis Program, the Wistar Institute, Philadelphia, PA, USA.
  • Auslander N; Molecular and Cellular Oncogenesis Program, the Wistar Institute, Philadelphia, PA, USA.
  • Dang CV; Molecular and Cellular Oncogenesis Program, the Wistar Institute, Philadelphia, PA, USA.
  • Abdel-Mohsen M; Ludwig Institute for Cancer Research, New York, NY, USA.
  • Kossenkov A; Immunology, Microenvironment and Metastasis Program, the Wistar Institute, Philadelphia, PA, USA.
  • Stanger BZ; Vaccine and Immunotherapy Center, the Wistar Institute, Philadelphia, PA, USA.
  • Shinde RS; Bioinformatics Facility, the Wistar Institute, Philadelphia, PA, USA.
Sci Immunol ; 7(75): eabn0704, 2022 09 09.
Article en En | MEDLINE | ID: mdl-36083892
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Microbioma Gastrointestinal Límite: Animals Idioma: En Revista: Sci Immunol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Microbioma Gastrointestinal Límite: Animals Idioma: En Revista: Sci Immunol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos