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Metabolomic Analysis and MRM Verification of Coarse and Fine Skin Tissues of Liaoning Cashmere Goat.
Xu, Yanan; Cai, Weidong; Chen, Rui; Zhang, Xinjiang; Bai, Zhixian; Zhang, Yu; Qin, Yuting; Gu, Ming; Sun, Yinggang; Wu, Yanzhi; Wang, Zeying.
Afiliación
  • Xu Y; College of Animal Science &Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
  • Cai W; College of Animal Science &Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
  • Chen R; College of Animal Science &Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
  • Zhang X; College of Animal Science &Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
  • Bai Z; College of Animal Science &Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
  • Zhang Y; College of Animal Science &Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
  • Qin Y; College of Animal Science &Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
  • Gu M; College of Animal Science &Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
  • Sun Y; College of Animal Science &Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
  • Wu Y; College of Animal Science &Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
  • Wang Z; College of Animal Science &Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
Molecules ; 27(17)2022 Aug 26.
Article en En | MEDLINE | ID: mdl-36080249
One of the critical elements in evaluating the quality of cashmere is its fineness, but we still know little about how it is regulated at the metabolic level. In this paper, we use UHPLC-MS/MS detection and analysis technology to compare the difference in metabolites between coarse cashmere (CT_LCG) and fine cashmere (FT_LCG) skin of Liaoning cashmere goats. According to the data, under positive mode four metabolites were significantly up-regulated and seven were significantly down-regulated. In negative mode, seven metabolites were significantly up-regulated and fourteen metabolites were significantly down-regulated. The two groups' most significant metabolites, Gly-Phe and taurochenodeoxycholate, may be crucial in controlling cashmere's growth, development, and fineness. In addition, we enriched six KEGG pathways, of which cholesterol metabolism, primary bile acid biosynthesis, and bile secretion were enriched in positive and negative modes. These findings offer a new research idea for further study into the critical elements influencing cashmere's fineness.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cabras / Espectrometría de Masas en Tándem Límite: Animals Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cabras / Espectrometría de Masas en Tándem Límite: Animals Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza