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Novel AR/AR-V7 and Mnk1/2 Degrader, VNPP433-3ß: Molecular Mechanisms of Action and Efficacy in AR-Overexpressing Castration Resistant Prostate Cancer In Vitro and In Vivo Models.
Thomas, Elizabeth; Thankan, Retheesh S; Purushottamachar, Puranik; Huang, Weiliang; Kane, Maureen A; Zhang, Yuji; Ambulos, Nicholas P; Weber, David J; Njar, Vincent C O.
Afiliación
  • Thomas E; Department of Pharmacology, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201, USA.
  • Thankan RS; The Center for Biomolecular Therapeutics, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201, USA.
  • Purushottamachar P; Department of Pharmacology, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201, USA.
  • Huang W; Flavocure Biotech, 701 E. Pratt St, Ste 2033, Baltimore, MD 21202, USA.
  • Kane MA; Isoprene Pharmaceuticals, Inc., 801 W Baltimore Street, Suite 502J, Baltimore, MD 21201, USA.
  • Zhang Y; Department of Pharmacology, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201, USA.
  • Ambulos NP; The Center for Biomolecular Therapeutics, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore, MD 21201, USA.
  • Weber DJ; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.
  • Njar VCO; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.
Cells ; 11(17)2022 08 30.
Article en En | MEDLINE | ID: mdl-36078112
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antagonistas de Receptores Androgénicos / Neoplasias de la Próstata Resistentes a la Castración Tipo de estudio: Prognostic_studies Límite: Humans / Male Idioma: En Revista: Cells Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antagonistas de Receptores Androgénicos / Neoplasias de la Próstata Resistentes a la Castración Tipo de estudio: Prognostic_studies Límite: Humans / Male Idioma: En Revista: Cells Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza