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Overexpression of nucleotide metabolic enzyme DUT in hepatocellular carcinoma potentiates a therapeutic opportunity through targeting its dUTPase activity.
Xu, Mingjing; Liu, Yue; Wan, Ho Lee; Wong, Alissa M; Ding, Xiaofan; You, Wenxing; Lo, Wing Sze; Ng, Kelvin K-C; Wong, Nathalie.
Afiliación
  • Xu M; Department of Surgery, Sir Y.K. Pao Centre for Cancer, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
  • Liu Y; Department of Surgery, Sir Y.K. Pao Centre for Cancer, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
  • Wan HL; Department of Surgery, Sir Y.K. Pao Centre for Cancer, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
  • Wong AM; Department of Surgery, Sir Y.K. Pao Centre for Cancer, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
  • Ding X; Department of Surgery, Sir Y.K. Pao Centre for Cancer, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
  • You W; Department of Surgery, Sir Y.K. Pao Centre for Cancer, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
  • Lo WS; Department of Surgery, Sir Y.K. Pao Centre for Cancer, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
  • Ng KK; Department of Surgery, Sir Y.K. Pao Centre for Cancer, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
  • Wong N; Department of Surgery, Sir Y.K. Pao Centre for Cancer, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China; State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Shatin, Hong Kong, China. Electronic address: natwong@cuhk.edu.hk.
Cancer Lett ; 548: 215898, 2022 11 01.
Article en En | MEDLINE | ID: mdl-36075487

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Límite: Humans Idioma: En Revista: Cancer Lett Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Irlanda

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Límite: Humans Idioma: En Revista: Cancer Lett Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Irlanda