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Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis.
Wei, Xing; Zhang, Li; Zhang, Yiqun; Cooper, Cody; Brewer, Chris; Tsai, Chia-Feng; Wang, Yi-Ting; Glaz, Micah; Wessells, Hunter B; Que, Jianwen; Titus, Mark A; Cirulli, Vincenzino; Glaser, Adam; Liu, Tao; Reder, Nicholas P; Creighton, Chad J; Xin, Li.
Afiliación
  • Wei X; Department of Urology, University of Washington, 850 Republican Street, Seattle, WA 98109, USA.
  • Zhang L; Department of Urology, University of Washington, 850 Republican Street, Seattle, WA 98109, USA.
  • Zhang Y; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
  • Cooper C; Alpenglow Biosciences, Inc., Seattle, WA 98103, USA.
  • Brewer C; Alpenglow Biosciences, Inc., Seattle, WA 98103, USA.
  • Tsai CF; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99354, USA.
  • Wang YT; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99354, USA.
  • Glaz M; Molecular Engineering and Sciences Institute, University of Washington, Seattle, WA 98109, USA.
  • Wessells HB; Department of Urology, University of Washington, 850 Republican Street, Seattle, WA 98109, USA.
  • Que J; Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA.
  • Titus MA; Department of Genitourinary Medical Oncology, MD Anderson Cancer Center, University of Texas, Houston TX 77030, USA.
  • Cirulli V; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98109, USA.
  • Glaser A; Department of Mechanical Engineering, University of Washington, Seattle, WA 98109, USA.
  • Liu T; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99354, USA.
  • Reder NP; Alpenglow Biosciences, Inc., Seattle, WA 98103, USA.
  • Creighton CJ; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
  • Xin L; Department of Urology, University of Washington, 850 Republican Street, Seattle, WA 98109, USA; Department of Genitourinary Medical Oncology, MD Anderson Cancer Center, University of Texas, Houston TX 77030, USA. Electronic address: xin18@uw.edu.
Cell Rep ; 40(10): 111313, 2022 09 06.
Article en En | MEDLINE | ID: mdl-36070687
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Próstata / Células del Estroma Límite: Animals Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Próstata / Células del Estroma Límite: Animals Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos