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Epstein-Barr virus-associated leiomyosarcoma of the larynx in an adult patient with human immunodeficiency virus infection: Case report and review of the literature.
Jin, Jian-Di; Chen, Zhe; Cao, Zai-Zai; Zhou, Shui-Hong; Zhang, Xiu-Ming; Yao, Hong-Tian.
Afiliación
  • Jin JD; Department of Infection, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China.
  • Chen Z; Department of Otolaryngology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China.
  • Cao ZZ; Department of Otolaryngology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China.
  • Zhou SH; Department of Otolaryngology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China.
  • Zhang XM; Department of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China.
  • Yao HT; Department of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China.
Head Neck ; 44(12): 2886-2903, 2022 12.
Article en En | MEDLINE | ID: mdl-36069494
We investigated the clinical features, treatment, and prognosis of laryngeal leiomyosarcoma (LLMS) and Epstein-Barr virus-associated (EBV-associated) LMS. We report a case of EBV-associated LLMS in an adult patient with HIV infection. We also conducted a review of the English-language literature on LLMS and EBV-associated leiomyosarcoma. To the best of our knowledge, 62 cases of LLMS and EBV-associated leiomyosarcoma have been reported to date. Of patients with LLS, 18.9% had distant metastases and 17.0% had local recurrence. The overall 5-year survival rate was 64.0%. Distant metastases affected the survival of patients with LLMS (p = 0.04). EBV-positive patients had a low survival rate (p = 0.01). Among patients with EBV-associated LMS, 8.2% had distant metastases and recurrence and the overall 5-year survival rate was 50.0%. EBV-associated LLMS is rare. The EBV infection might be a poor prognostic factor of LLMS.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Infecciones por Virus de Epstein-Barr / Laringe / Leiomiosarcoma Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Humans Idioma: En Revista: Head Neck Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Infecciones por Virus de Epstein-Barr / Laringe / Leiomiosarcoma Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Humans Idioma: En Revista: Head Neck Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos