Platyconic acid A­induced PPM1A upregulation inhibits the proliferation, inflammation and extracellular matrix deposition of TGF­ß1­induced lung fibroblasts.

Su, Chengcheng; Tang, Yanfen; Wang, Cong; Huang, Haifeng; Hou, Haihui

Platyconic acid Ainduced PPM1A upregulation inhibits the proliferation, inflammation and extracellular matrix deposition of TGFß1induced lung fibroblasts.

Su, Chengcheng; Tang, Yanfen; Wang, Cong; Huang, Haifeng; Hou, Haihui.

Afiliación

Su C; Pneumology Department, Nantong Hospital of Traditional Chinese Medicine, Nantong Affiliated Hospital of Nanjing University of Chinese Medicine, Nantong, Jiangsu 226500, P.R. China.
Tang Y; Pneumology Department, Nantong Hospital of Traditional Chinese Medicine, Nantong Affiliated Hospital of Nanjing University of Chinese Medicine, Nantong, Jiangsu 226500, P.R. China.
Wang C; Pneumology Department, Nantong Hospital of Traditional Chinese Medicine, Nantong Affiliated Hospital of Nanjing University of Chinese Medicine, Nantong, Jiangsu 226500, P.R. China.
Huang H; Pneumology Department, Nantong Hospital of Traditional Chinese Medicine, Nantong Affiliated Hospital of Nanjing University of Chinese Medicine, Nantong, Jiangsu 226500, P.R. China.
Hou H; Pneumology Department, Nantong Hospital of Traditional Chinese Medicine, Nantong Affiliated Hospital of Nanjing University of Chinese Medicine, Nantong, Jiangsu 226500, P.R. China.

Mol Med Rep ; 26(5)2022 11.

Article en En | MEDLINE | ID: mdl-36069235

Asunto(s)

Fibrosis Pulmonar; Saponinas; Proliferación Celular; Matriz Extracelular/metabolismo; Fibroblastos/metabolismo; Humanos; Inflamación/metabolismo; Pulmón/metabolismo; Proteína Fosfatasa 2C/genética; Proteína Fosfatasa 2C/metabolismo; Fibrosis Pulmonar/metabolismo; ARN Mensajero/metabolismo; Saponinas/farmacología; Factor de Crecimiento Transformador beta1/metabolismo; Triterpenos; Regulación hacia Arriba; beta Catenina/metabolismo

Palabras clave

SMAD/ßcatenin signaling; platyconic acid A; protein phosphatase Mg2+/Mn2+-dependent 1A; pulmonary fibrosis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fibrosis Pulmonar / Saponinas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Mol Med Rep Año: 2022 Tipo del documento: Article Pais de publicación: Grecia

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