The elevated D-2-hydroxyglutarate level found as a characteristic metabolic change of colon cancer in both in vitro and in vivo models.

Atalay, Esra Bulut; Kayali, Hulya Ayar

The elevated D-2-hydroxyglutarate level found as a characteristic metabolic change of colon cancer in both in vitro and in vivo models.

Atalay, Esra Bulut; Kayali, Hulya Ayar.

Afiliación

Atalay EB; Izmir Biomedicine and Genome Center, 35340, Izmir, Turkey; Izmir International Biomedicine and Genome Institute, Dokuz Eylül University, 35340, Izmir, Turkey.
Kayali HA; Izmir Biomedicine and Genome Center, 35340, Izmir, Turkey; Izmir International Biomedicine and Genome Institute, Dokuz Eylül University, 35340, Izmir, Turkey; Department of Chemistry, Division of Biochemistry, Faculty of Science, Dokuz Eylul University, Izmir, 35160, Turkey. Electronic address: hulya.ayarkayali@gmail.com.

Biochem Biophys Res Commun ; 627: 191-199, 2022 10 30.

Article en En | MEDLINE | ID: mdl-36049357

Asunto(s)

Adenocarcinoma; Neoplasias del Colon; Células CACO-2; Glucosa/metabolismo; Glutaratos; Humanos; Isocitrato Deshidrogenasa/metabolismo; Ácido Pirúvico

Palabras clave

2-Hydroxyglutarate; Colon cancer; Cori cycle; Metabolism; TCA cycle; wt-IDH1/2

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adenocarcinoma / Neoplasias del Colon Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2022 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos

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