Targeting Wnt/ß-catenin signaling pathway in triple-negative breast cancer by benzylic organotrisulfides: Contribution of the released hydrogen sulfide towards potent anti-cancer activity.

Bhattacherjee, Debojit; Raina, Khyati; Mandal, Tapas K; Thummer, Rajkumar P; Bhabak, Krishna P

Bhattacherjee, Debojit; Raina, Khyati; Mandal, Tapas K; Thummer, Rajkumar P; Bhabak, Krishna P.

Afiliación

Bhattacherjee D; Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India; Centre for the Environment, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India.
Raina K; Department Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India.
Mandal TK; Centre for the Environment, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India; Department of Chemical Engineering, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India; Jyoti and Bhupat Mehta School of Health Sciences and Technology, Indian Institute of Techn
Thummer RP; Department Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India. Electronic address: rthu@iitg.ac.in.
Bhabak KP; Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India; Centre for the Environment, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India; Jyoti and Bhupat Mehta School of Health Sciences and Technology, Indian Institute of Technology Guwah

Free Radic Biol Med ; 191: 82-96, 2022 10.

Article en En | MEDLINE | ID: mdl-36038037

Asunto(s)

Sulfuro de Hidrógeno; Neoplasias de la Mama Triple Negativas; Apoptosis; Línea Celular Tumoral; Proliferación Celular; Ciclina D1/genética; Ciclina D1/metabolismo; Glucógeno Sintasa Quinasa 3 beta/metabolismo; Humanos; Sulfuro de Hidrógeno/metabolismo; Sulfuro de Hidrógeno/farmacología; Neoplasias de la Mama Triple Negativas/tratamiento farmacológico; Neoplasias de la Mama Triple Negativas/metabolismo; Proteína p53 Supresora de Tumor/metabolismo; Vía de Señalización Wnt; beta Catenina/genética; beta Catenina/metabolismo

Palabras clave

Anti-cancer activity; Hydrogen sulfide donors; Organotrisulfides; Triple-negative breast cancer; Wnt/ß-catenin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama Triple Negativas / Sulfuro de Hidrógeno Límite: Humans Idioma: En Revista: Free Radic Biol Med Asunto de la revista: BIOQUIMICA / MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos

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