A new use for old drugs: identifying compounds with an anti-obesity effect using a high through-put semi-automated <i>Caenorhabditis elegans</i> screening platform.

Haerkens, Freek; Kikken, Charlotte; Kirkels, Laurens; van Amstel, Monique; Wouters, Willemijn; van Doornmalen, Els; Francke, Christof; Hughes, Samantha

A new use for old drugs: identifying compounds with an anti-obesity effect using a high through-put semi-automated Caenorhabditis elegans screening platform.

Haerkens, Freek; Kikken, Charlotte; Kirkels, Laurens; van Amstel, Monique; Wouters, Willemijn; van Doornmalen, Els; Francke, Christof; Hughes, Samantha.

Afiliación

Haerkens F; BioCentre, HAN University of Applied Sciences, 6525EM, Nijmegen, the Netherlands.
Kikken C; BioCentre, HAN University of Applied Sciences, 6525EM, Nijmegen, the Netherlands.
Kirkels L; BioCentre, HAN University of Applied Sciences, 6525EM, Nijmegen, the Netherlands.
van Amstel M; Now at the Donders Institute for Brain, Cognition and Behaviour, Radboud University, 6525 AJ, Nijmegen, the Netherlands.
Wouters W; Pivot Park Screening Centre, 5349AB, Oss, the Netherlands.
van Doornmalen E; Pivot Park Screening Centre, 5349AB, Oss, the Netherlands.
Francke C; Pivot Park Screening Centre, 5349AB, Oss, the Netherlands.
Hughes S; BioCentre, HAN University of Applied Sciences, 6525EM, Nijmegen, the Netherlands.

Heliyon ; 8(8): e10108, 2022 Aug.

Article en En | MEDLINE | ID: mdl-36033279

Palabras clave

C. elegans; High-throughput screening; Obesity; Prestwick chemical library; Repurposing drugs

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: Heliyon Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido

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