Mannitol as an Excipient for Lyophilized Injectable Formulations.

Thakral, Seema; Sonje, Jayesh; Munjal, Bhushan; Bhatnagar, Bakul; Suryanarayanan, Raj

Thakral, Seema; Sonje, Jayesh; Munjal, Bhushan; Bhatnagar, Bakul; Suryanarayanan, Raj.

Afiliación

Thakral S; Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, United States of America. Electronic address: seema.thakral@boehringer-ingelheim.com.
Sonje J; Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, United States of America.
Munjal B; Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, United States of America.
Bhatnagar B; Pfizer Inc., BioTherapeutics, Pharmaceutical Sciences, 1 Burtt Road, Andover, MA 01810, United States of America.
Suryanarayanan R; Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, United States of America. Electronic address: surya001@umn.edu.

J Pharm Sci ; 112(1): 19-35, 2023 01.

Article en En | MEDLINE | ID: mdl-36030846

Asunto(s)

Excipientes; Manitol; Excipientes/química; Manitol/química; Liofilización/métodos; Composición de Medicamentos; Congelación; Sacarosa/química; Rastreo Diferencial de Calorimetría

Palabras clave

Bulking agent; Differential scanning calorimetry (DSC); Excipients; Hydrate(s); Injectables; Lyophilization; Mannitol; Polymorphs; Sucrose; Trehalose; X-ray Powder diffraction (XRD)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Excipientes / Manitol Idioma: En Revista: J Pharm Sci Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

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