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Platelet lysate and tendon healing: comparative analysis of autologous frozen-thawed PRP and ketorolac tromethamine in the treatment of patients with rotator cuff tendinopathy.
Markazi, Raha; Soltani-Zangbar, Mohammad Sadegh; Zamani, Majid; Eghbal-Fard, Shadi; Motavalli, Roza; Kamrani, Amin; Dolati, Sanam; Ahmadi, Majid; Aghebati-Maleki, Leili; Mehdizadeh, Amir; Eslamian, Fariba; Pishgahi, Alireza; Yousefi, Mehdi.
Afiliación
  • Markazi R; Physical Medicine and Rehabilitation Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Soltani-Zangbar MS; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Zamani M; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Eghbal-Fard S; Department of Immunology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Motavalli R; Department of Medical Laboratory Sciences, Faculty of Allied Medicine, Infectious Diseases Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
  • Kamrani A; Department of Immunology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Dolati S; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Ahmadi M; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Aghebati-Maleki L; Physical Medicine and Rehabilitation Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Mehdizadeh A; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Eslamian F; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Pishgahi A; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Yousefi M; Physical Medicine and Rehabilitation Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Growth Factors ; 40(5-6): 163-174, 2022 11.
Article en En | MEDLINE | ID: mdl-36026559
Platelet-rich blood derivatives are being nowadays increasingly used in the treatment of tendon-related pathologies as a rich source of growth factors. We sought to ascertain if local application of platelet lysate (PL) to augment rotator cuff repair ameliorates patient outcomes compared to ketorolac tromethamine treated group. A total of forty patients, with clinical diagnosis of Rotator Cuff Tendinopathy were randomized to receive sub acromial injections of PL every week for a total of 3 injections and two injection of ketorolac tromethamine once every two weeks. Subjective assessments included VAS, SPADI and shoulder range of motion were assessed at baseline and at 1 and 6 months after injection. Taking both control and PL groups, it was vividly seen that the outcomes were identical at the initial state, as well as the short-term one; whereas, when considering the 6-month period, there is a seemingly remarkable superiority in PL group in all parameters.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tendinopatía / Plasma Rico en Plaquetas / Lesiones del Manguito de los Rotadores Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Growth Factors Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tendinopatía / Plasma Rico en Plaquetas / Lesiones del Manguito de los Rotadores Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Growth Factors Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido