Lesions of experimentally induced Tyzzer's disease in Syrian hamsters, guineapigs, mice and rats.
Lab Anim
; 21(2): 155-60, 1987 Apr.
Article
en En
| MEDLINE
| ID: mdl-3599878
The relative susceptibilities of C57BL/6NCR and BALB/cANNCR mice, F344/NCR rats, 2/NCR guineapigs and CR:RGH Syrian hamsters to Bacillus piliformis infection were determined by orally inoculating 20 weanling females from each species with suspensions of B. piliformis spores. Animals from each group were sequentially necropsied over 2 week periods to document the lesions produced. No significant gross or microscopic lesions were observed in the BALB mice or the Fischer rats. Gross and microscopic lesions were observed in the livers and intestines of many guineapigs and hamsters killed 3-14 days after inoculation. A large lesion was observed in the left cardiac ventricle of one C57BL mouse 10 days after inoculation. Warthin-Starry silver-stained tissue sections revealed clusters of B. piliformis within the cytoplasm of intestinal epithelial cells, smooth muscle cells, hepatocytes and myocytes bordering foci of necrosis in the intestines, liver and heart.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones Bacterianas
/
Hepatitis Animal
/
Hepatitis Viral Animal
Límite:
Animals
Idioma:
En
Revista:
Lab Anim
Año:
1987
Tipo del documento:
Article
Pais de publicación:
Reino Unido