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The reliability of P300 and the influence of age, gender and education variables in a 50 years and older normative sample.
Yerlikaya, Deniz; Hünerli-Gündüz, Duygu; Fide, Ezgi; Özbek, Yagmur; Kiyi, Ilayda; Öztura, Ibrahim; Yener, Görsev G.
Afiliación
  • Yerlikaya D; Department of Neurosciences, Institute of Health Sciences, Dokuz Eylül University, 35340 Izmir, Turkey.
  • Hünerli-Gündüz D; Department of Neurosciences, Institute of Health Sciences, Dokuz Eylül University, 35340 Izmir, Turkey.
  • Fide E; Department of Neurosciences, Institute of Health Sciences, Dokuz Eylül University, 35340 Izmir, Turkey.
  • Özbek Y; Department of Neurosciences, Institute of Health Sciences, Dokuz Eylül University, 35340 Izmir, Turkey.
  • Kiyi I; Department of Neurosciences, Institute of Health Sciences, Dokuz Eylül University, 35340 Izmir, Turkey.
  • Öztura I; Department of Neurology, Dokuz Eylül University Medical School, 35340 Izmir, Turkey; Brain Dynamics Multidisciplinary Research Center, Dokuz Eylül University, 35340 Izmir, Turkey. Electronic address: ibrahim.oztura@deu.edu.tr.
  • Yener GG; Brain Dynamics Multidisciplinary Research Center, Dokuz Eylül University, 35340 Izmir, Turkey; Izmir University of Economics, Faculty of Medicine, 35330 Izmir, Turkey; Izmir International Biomedicine and Genome Institute, Dokuz Eylul University, Izmir, Turkey. Electronic address: gorsev.yener@ieu.ed
Int J Psychophysiol ; 181: 1-13, 2022 11.
Article en En | MEDLINE | ID: mdl-35988895
OBJECTIVES: The present study aims to investigate the effects of age, gender, and level of education on P300 in a healthy population, aged 50 years and over; and determine the reliability metrics for different conditions and measurement methods. METHOD: Auditory and visual oddball recordings of 171 healthy adults were investigated. A fully automated preprocessing was applied to elicit ERP P300. Maximum peak amplitude, latency and mean amplitudes were measured. Data were stratified by age, gender, and education to determine group-level differences by using repeat measures of ANOVA. The internal consistency of P300 was calculated by a split-half method using odd-even segments. Test-retest reliability was assessed by calculating the intraclass correlation coefficient (ICC). RESULTS: Maximum peak P300 amplitudes were higher in the 50-64 years age group compared to the >65 years age group; and females showed increased P300 amplitudes compared to males. P300 measures showed fair to good internal consistency and poor to good test-retest reliability. CONCLUSION: Age and gender should be taken into account when designing ERP studies with elderly individuals. P300 showed good internal consistency in general, between gender groups and age groups. Long-term test-retest reliability was lower but acceptable. These findings can be interpreted as the strength of P300 by being an objective and reliable method independent of cultural differences. Here we underline several factors that may affect P300 measures and discuss other possible factors that should be standardized for P300 to be used in clinical settings.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Potenciales Relacionados con Evento P300 / Potenciales Evocados Auditivos Aspecto: Determinantes_sociais_saude Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Psychophysiol Año: 2022 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Potenciales Relacionados con Evento P300 / Potenciales Evocados Auditivos Aspecto: Determinantes_sociais_saude Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Psychophysiol Año: 2022 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Países Bajos