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Source recognition discriminability impairment in Huntington's versus Alzheimer's disease: Evidence from the CVLT-3.
Graves, Lisa V; Churchill, Emma G; Williams, McKenna E; Van Etten, Emily J; Bondi, Mark W; Salmon, David P; Corey-Bloom, Jody; Delis, Dean C; Gilbert, Paul E.
Afiliación
  • Graves LV; Department of Psychology, California State University San Marcos, San Marcos, CA, USA.
  • Churchill EG; Department of Psychology, San Diego State University, San Diego, CA, USA.
  • Williams ME; SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA.
  • Van Etten EJ; Department of Psychology, University of Arizona, Tucson, AZ, USA.
  • Bondi MW; Veterans Affairs San Diego Healthcare System, San Diego, CA, USA.
  • Salmon DP; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Corey-Bloom J; Department of Neurosciences, University of California San Diego, La Jolla, CA, USA.
  • Delis DC; Department of Neurosciences, University of California San Diego, La Jolla, CA, USA.
  • Gilbert PE; Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA, USA.
Appl Neuropsychol Adult ; : 1-6, 2022 Aug 19.
Article en En | MEDLINE | ID: mdl-35984776
Research suggests that individuals with Huntington's disease (HD) perform better than individuals with Alzheimer's disease (AD) on the California Verbal Learning Test (CVLT) Yes/No Recognition trial. However, those with HD have been shown to have deficits comparable to those with AD on the Source Recognition Discriminability (RD) index (which assesses the ability to distinguish between List A targets and List B distractors), suggesting that HD may involve selective impairment in aspects of yes/no recognition that rely on source memory. However, whether individuals with HD and AD show comparable deficits on Source RD across stages of dementia severity has not been adequately investigated. We examined performance on the CVLT-3 List A vs. List B RD index in individuals with HD or AD and mild or moderate dementia. Among individuals with mild dementia, scores were higher in the HD versus AD group, whereas among individuals with moderate dementia, scores were comparable between the HD and AD groups; this corresponded to differential performance across dementia stages among individuals with HD, but not AD. The present findings suggest that, relative to AD, HD may be associated with disproportionate decline in aspects of yes/no recognition that rely on source memory.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Appl Neuropsychol Adult Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Appl Neuropsychol Adult Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos