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Sonographic evaluation of subclinical entheseal involvement in patients with hypoparathyroidism: a case control study.
Firat, S N; Kuskonmaz, S M; Önder, Ç E; Omma, T; Genç, H; Çulha, C.
Afiliación
  • Firat SN; Department of Endocrinology and Metabolism, University of Health Sciences Ankara Training and Research Hospital, HacettepeMah., Ulucanlar Cad., Altindag, 06230, Ankara, Turkey. sevdenursuruc@yahoo.com.
  • Kuskonmaz SM; Department of Endocrinology and Metabolism, University of Health Sciences Ankara Training and Research Hospital, HacettepeMah., Ulucanlar Cad., Altindag, 06230, Ankara, Turkey.
  • Önder ÇE; Department of Endocrinology and Metabolism, Nigde Ömer Halisdemir University Training and Research Hospital, Nigde, Turkey.
  • Omma T; Department of Endocrinology and Metabolism, University of Health Sciences Ankara Training and Research Hospital, HacettepeMah., Ulucanlar Cad., Altindag, 06230, Ankara, Turkey.
  • Genç H; Department of Physical Medicine and Rehabilitation, University of Health Sciences Ankara Training and Research Hospital, Ankara, Turkey.
  • Çulha C; Department of Endocrinology and Metabolism, University of Health Sciences Ankara Training and Research Hospital, HacettepeMah., Ulucanlar Cad., Altindag, 06230, Ankara, Turkey.
J Endocrinol Invest ; 46(1): 133-139, 2023 Jan.
Article en En | MEDLINE | ID: mdl-35982371
PURPOSE: Hypoparathyroidism is a disease characterized by low serum calcium, increased serum phosphorus and low PTH levels. Although patients are treated with active vitamin D and calcium, a proper serum calcium phosphorus balance cannot always be achieved. Ectopic calcifications that develop in organs during treatment are the most common complications. To date, there is not any published study on enthesopathy in patients with hypoparathyroidism. The aim of this study was to evaluate subclinical enthesopathy in patients with hypoparathyroidism with ultrasound and to compare the results with those of the control group. METHODS: The study included patients aged 18-65 years with postoperative hypoparathyroidism and hypothyroidism (group hypoP + hypoT), patients with postoperative hypothyroidism (group hypoT), and healthy age and sex-matched volunteers (group C). Ultrasonographic findings of enthesopathy in both extremities were documented according to the Glasgow Ultrasound Enthesitis Scoring System (GUESS). RESULTS: GUESS scores in group hypoP + hypoT, were significantly higher when compared to the other groups. There was a statistically significant correlation between the total GUESS scores and total enthesophyte scores and the duration of hypoparathyroidism (p < 0.05, r = 0.43) (p < 0.05, r = 0.39) respectively. In the correlation analysis of all groups, a significant negative correlation was found between serum Ca and PTH levels and the total GUESS scores (p < 0.01, r = - 0.37; p < 0.01, r = - 0.54, respectively). CONCLUSION: This study showed that GUESS scores were significantly higher in patients with hypoparathyroidism compared to those with hypothyroidism and control subjects. GUESS scores were positively correlated with disease duration. Patients with hypoparathyroidism need to be evaluated for subclinical enthesopathy during follow-up.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Entesopatía / Hipoparatiroidismo / Hipotiroidismo Tipo de estudio: Observational_studies Límite: Humans Idioma: En Revista: J Endocrinol Invest Año: 2023 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Entesopatía / Hipoparatiroidismo / Hipotiroidismo Tipo de estudio: Observational_studies Límite: Humans Idioma: En Revista: J Endocrinol Invest Año: 2023 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Italia