SJPYT-195: A Designed Nuclear Receptor Degrader That Functions as a Molecular Glue Degrader of GSPT1.

Huber, Andrew D; Li, Yongtao; Lin, Wenwei; Galbraith, Annalise N; Mishra, Ashutosh; Porter, Shaina N; Wu, Jing; Florke Gee, Rebecca R; Zhuang, Wei; Pruett-Miller, Shondra M; Peng, Junmin; Chen, Taosheng

Huber, Andrew D; Li, Yongtao; Lin, Wenwei; Galbraith, Annalise N; Mishra, Ashutosh; Porter, Shaina N; Wu, Jing; Florke Gee, Rebecca R; Zhuang, Wei; Pruett-Miller, Shondra M; Peng, Junmin; Chen, Taosheng.

Afiliación

Huber AD; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Li Y; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Lin W; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Galbraith AN; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Mishra A; Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Porter SN; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Wu J; Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Florke Gee RR; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Zhuang W; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Pruett-Miller SM; Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Peng J; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Chen T; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.

ACS Med Chem Lett ; 13(8): 1311-1320, 2022 Aug 11.

Article en En | MEDLINE | ID: mdl-35978691

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: ACS Med Chem Lett Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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