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A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer.
Goldberg, Manijeh; Manzi, Aaron; Birdi, Amritpreet; Laporte, Brandon; Conway, Peter; Cantin, Stefanie; Mishra, Vasudha; Singh, Alka; Pearson, Alexander T; Goldberg, Eric R; Goldberger, Sam; Flaum, Benjamin; Hasina, Rifat; London, Nyall R; Gallia, Gary L; Bettegowda, Chetan; Young, Simon; Sandulache, Vlad; Melville, James; Shum, Jonathan; O'Neill, Sonya E; Aydin, Erkin; Zhavoronkov, Alex; Vidal, Anxo; Soto, Atenea; Alonso, Maria Jose; Rosenberg, Ari J; Lingen, Mark W; D'Cruz, Anil; Agrawal, Nishant; Izumchenko, Evgeny.
Afiliación
  • Goldberg M; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. mgoldberg@privotechnologies.com.
  • Manzi A; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA. mgoldberg@privotechnologies.com.
  • Birdi A; Department of Biomedical Engineering, University of Massachusetts Lowell, Lowell, MA, USA. mgoldberg@privotechnologies.com.
  • Laporte B; Privo Technologies, Peabody, MA, USA. mgoldberg@privotechnologies.com.
  • Conway P; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Cantin S; Department of Biomedical Engineering, University of Massachusetts Lowell, Lowell, MA, USA.
  • Mishra V; Privo Technologies, Peabody, MA, USA.
  • Singh A; Privo Technologies, Peabody, MA, USA.
  • Pearson AT; Privo Technologies, Peabody, MA, USA.
  • Goldberg ER; Privo Technologies, Peabody, MA, USA.
  • Goldberger S; Privo Technologies, Peabody, MA, USA.
  • Flaum B; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL, USA.
  • Hasina R; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL, USA.
  • London NR; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL, USA.
  • Gallia GL; Privo Technologies, Peabody, MA, USA.
  • Bettegowda C; Privo Technologies, Peabody, MA, USA.
  • Young S; Privo Technologies, Peabody, MA, USA.
  • Sandulache V; Department of Surgery, Section of Otolaryngology-Head and Neck Surgery, University of Chicago, Chicago, IL, USA.
  • Melville J; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Shum J; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • O'Neill SE; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Aydin E; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Zhavoronkov A; Department of Neurosurgery and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Vidal A; Department of Oral Maxillofacial Surgery, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Soto A; Department of Otolaryngology-Head & Neck Surgery, Baylor College of Medicine, Houston, TX, USA.
  • Alonso MJ; Department of Oral Maxillofacial Surgery, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Rosenberg AJ; Department of Oral Maxillofacial Surgery, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Lingen MW; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • D'Cruz A; Massachusetts College of Pharmacy and Health Sciences, Boston, MA, USA.
  • Agrawal N; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Izumchenko E; Insilico Medicine, Pak Shek Kok, Hong Kong.
Nat Commun ; 13(1): 4829, 2022 08 17.
Article en En | MEDLINE | ID: mdl-35977936
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Boca / Carcinoma de Células Escamosas / Neoplasias de Cabeza y Cuello Aspecto: Patient_preference Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Boca / Carcinoma de Células Escamosas / Neoplasias de Cabeza y Cuello Aspecto: Patient_preference Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido