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Contrast Enhanced Mammography in Routine Clinical Practice: Frequency and Malignancy Rates of Enhancing Otherwise Occult Findings.
Viggiano, Taylor; Scott, Ryan; Sharpe, Richard; Kasper, Catherine; Mazza, Gina; Pizzitola, Victor; Giurescu, Marina; Lorans, Roxanne; Eversman, William; Patel, Bhavika K.
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  • Viggiano T; Mayo Clinic Alix School of Medicine, Mayo Clinic, Phoenix, AZ.
  • Scott R; Division of Radiology, Mayo Clinic Arizona, Northwestern Medical Group, Grayslake IL.
  • Sharpe R; Division of Radiology, Mayo Clinic Arizona, Northwestern Medical Group, Grayslake IL.
  • Kasper C; Division of Radiology, Mayo Clinic Arizona, Self Regional Healthcare, Greenwood, SC.
  • Mazza G; Division of Health Sciences Research, Mayo Clinic Arizona.
  • Pizzitola V; Division of Radiology, Mayo Clinic Arizona, Northwestern Medical Group, Grayslake IL.
  • Giurescu M; Division of Radiology, Mayo Clinic Arizona, Northwestern Medical Group, Grayslake IL.
  • Lorans R; Division of Radiology, Mayo Clinic Arizona, Northwestern Medical Group, Grayslake IL.
  • Eversman W; Division of Radiology, Mayo Clinic Arizona, Northwestern Medical Group, Grayslake IL.
  • Patel BK; Division of Radiology, Mayo Clinic Arizona, Northwestern Medical Group, Grayslake IL. Electronic address: Patel.Bhavika@mayo.edu.
Clin Breast Cancer ; 22(7): e736-e744, 2022 10.
Article en En | MEDLINE | ID: mdl-35977855
BACKGROUND: In routine clinical practice, contrast-enhanced mammography (CEM) examinations identify enhancing findings seen only on subtraction images that have no low-energy mammographic or sonographic correlate. The purpose of this study is to report the frequency and malignancy rates of enhancing findings seen only on subtraction images in a tertiary care breast imaging practice. MATERIALS AND METHODS: Consecutive review of CEM exams from December 2015 to May 2020. Chi square tests were used to determine associations between cancer diagnosis and clinical characteristics of enhancing findings seen only on subtraction images, P < .05 indicating a statistically significant difference. RESULTS: Four percent (100/2464) of CEM examinations identified 108 enhancing findings seen only on subtraction images. Twenty of those CEM enhancing findings were directly managed as a multifocal disease. Of those further evaluated with MR, 23% (19/78) with associated MR correlates were treated surgically as presumed multicentric or multifocal disease following multidisciplinary review. The remaining 76% (59/78) of enhancing findings were seen only on subtraction images, these included: 20% (12/59) and downgraded to benign on MR 80% (47/59) with suspicious findings which underwent MR vacuum assisted breast biopsy yielding: 26% (12/47) malignancy, 9% (4/47) high risk, and 66% (31/47) benign diagnoses. CONCLUSION: Enhancing findings seen on subtraction only CEM images are seen in 4% of cases in clinical practice. MR correlation can help characterize CEM findings to: (1) avoid unnecessary biopsy for benign findings, and (2) guide tissue sampling or empiric surgical planning for suspicious findings.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Medios de Contraste Tipo de estudio: Clinical_trials / Diagnostic_studies / Prognostic_studies Límite: Female / Humans Idioma: En Revista: Clin Breast Cancer Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Medios de Contraste Tipo de estudio: Clinical_trials / Diagnostic_studies / Prognostic_studies Límite: Female / Humans Idioma: En Revista: Clin Breast Cancer Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos