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SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis.
Pranzini, Erica; Pardella, Elisa; Muccillo, Livio; Leo, Angela; Nesi, Ilaria; Santi, Alice; Parri, Matteo; Zhang, Tong; Uribe, Alejandro Huerta; Lottini, Tiziano; Sabatino, Lina; Caselli, Anna; Arcangeli, Annarosa; Raugei, Giovanni; Colantuoni, Vittorio; Cirri, Paolo; Chiarugi, Paola; Maddocks, Oliver D K; Paoli, Paolo; Taddei, Maria Letizia.
Afiliación
  • Pranzini E; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy. Electronic address: erica.pranzini@unifi.it.
  • Pardella E; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
  • Muccillo L; Department of Sciences and Technologies, University of Sannio, Via Francesco de Sanctis, 82100 Benevento, Italy.
  • Leo A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
  • Nesi I; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
  • Santi A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
  • Parri M; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
  • Zhang T; Institute of Cancer Sciences, Wolfson Wohl Cancer Research Centre, University of Glasgow, Switchback Road, Glasgow G61 1QH, UK; Novartis Institutes for BioMedical Research, Shanghai, China.
  • Uribe AH; Institute of Cancer Sciences, Wolfson Wohl Cancer Research Centre, University of Glasgow, Switchback Road, Glasgow G61 1QH, UK.
  • Lottini T; Department of Experimental and Clinical Medicine, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
  • Sabatino L; Department of Sciences and Technologies, University of Sannio, Via Francesco de Sanctis, 82100 Benevento, Italy.
  • Caselli A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
  • Arcangeli A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
  • Raugei G; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
  • Colantuoni V; Department of Sciences and Technologies, University of Sannio, Via Francesco de Sanctis, 82100 Benevento, Italy.
  • Cirri P; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
  • Chiarugi P; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
  • Maddocks ODK; Institute of Cancer Sciences, Wolfson Wohl Cancer Research Centre, University of Glasgow, Switchback Road, Glasgow G61 1QH, UK.
  • Paoli P; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy. Electronic address: paolo.paoli@unifi.it.
  • Taddei ML; Department of Experimental and Clinical Medicine, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Cell Rep ; 40(7): 111233, 2022 08 16.
Article en En | MEDLINE | ID: mdl-35977477

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Neoplasias Límite: Humans Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Neoplasias Límite: Humans Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos