Your browser doesn't support javascript.
loading
In vitro antiviral effect of Mexican and Brazilian propolis and phenolic compounds against human coronavirus 229E.
Silva-Beltrán, Norma Patricia; Galvéz-Ruíz, Juan Carlos; Ikner, Luisa A; Umsza-Guez, Marcelo Andrés; de Paula Castro, Thiago Luiz; Gerba, Charles P.
Afiliación
  • Silva-Beltrán NP; Departmento de Ciencias de la Salud, Universidad de Sonora, Ciudad Obregón, México.
  • Galvéz-Ruíz JC; Departamento de Ciencias Químico Biológicas, Universidad deSonora, Hermosillo, México.
  • Ikner LA; Department of Environmental Science, University of Arizona, Water Energy Sustainable Technology (WEST) Center, Tucson, AZ, USA.
  • Umsza-Guez MA; Departamento do Biotecnología, Universidade Federal da Bahía, Salvador, Brazil.
  • de Paula Castro TL; Departamento do Biotecnología, Universidade Federal da Bahía, Salvador, Brazil.
  • Gerba CP; Department of Environmental Science, University of Arizona, Water Energy Sustainable Technology (WEST) Center, Tucson, AZ, USA.
Int J Environ Health Res ; 33(12): 1591-1603, 2023 Dec.
Article en En | MEDLINE | ID: mdl-35951754
Propolis is a resinous substance collected by bees (Apis mellifera). It is used for its biological properties. This natural product is available as a safe therapeutic option. Herein, we report the antiviral effects of brown propolis extract from Mexico and green and red propolis extracts from Brazil, as well as their phenolic compounds (quercetin, caffeic acid, and rutin) in preventing infection of MRC-5 cells by HCoV-229E. Normal human fibroblast lung cells (MRC-5) were used to determine the cytotoxicity of the compounds. All samples studied showed antiviral activity. Green and brown propolis extracts, and quercetin exhibited the best EC50 values with values of 19.080, 11.240, and 77.208 µg/mL against HCoV-229E, respectively, and with TC50 of 62.19, 29.192, and 298 µg/mL on MRC-5 cells, respectively. These results are the first in vitro study of the effects of propolis on HCoV-229E and provide the basis for the development of natural formulations against other coronavirus strains.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Própolis / Coronavirus Humano 229E Límite: Animals / Humans País/Región como asunto: America do sul / Brasil / Mexico Idioma: En Revista: Int J Environ Health Res Asunto de la revista: SAUDE AMBIENTAL Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Própolis / Coronavirus Humano 229E Límite: Animals / Humans País/Región como asunto: America do sul / Brasil / Mexico Idioma: En Revista: Int J Environ Health Res Asunto de la revista: SAUDE AMBIENTAL Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido