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The Drug Coated Balloon-Only Strategy for Treatment of de Novo Left Main Coronary Artery Bifurcation Lesion: Stentless Strategy.
Liu, Hengdao; Zhao, Yanyan; Lu, Yang; Zhou, Shilong; Zhang, Yubin; Zhao, Junwei; Yang, Huilin; Xing, Junhui; Feng, Ruihan; Xue, XiaoFei; Tao, Hailong; Song, Ruipeng; Gu, Heping.
Afiliación
  • Liu H; Department of Cardiology, 191599Zhengzhou University First Affiliated Hospital, Zhengzhou, Henan, China.
  • Zhao Y; Department of Cardiology, 191599Zhengzhou University First Affiliated Hospital, Zhengzhou, Henan, China.
  • Lu Y; Department of Emergency, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
  • Zhou S; Department of Cardiology, 191599Zhengzhou University First Affiliated Hospital, Zhengzhou, Henan, China.
  • Zhang Y; Department of Cardiology, 191599Zhengzhou University First Affiliated Hospital, Zhengzhou, Henan, China.
  • Zhao J; Department of Cardiology, Yexian People's Hospital, Pingdingshan, Henan, China.
  • Yang H; Department of Cardiology, Nanle people's Hospital, Puyang, Henan, China.
  • Xing J; Department of Cardiology, 191599Zhengzhou University First Affiliated Hospital, Zhengzhou, Henan, China.
  • Feng R; Department of Cardiology, Xinxiang Central Hospital, Xinxiang, Henan, China.
  • Xue X; Department of Cardiology, 191599Zhengzhou University First Affiliated Hospital, Zhengzhou, Henan, China.
  • Tao H; Department of Cardiology, 191599Zhengzhou University First Affiliated Hospital, Zhengzhou, Henan, China.
  • Song R; Department of Endocrinology, The Third People's Provincial Hospital of Henan Province, Zhengzhou, Henan, China.
  • Gu H; Department of Cardiology, 191599Zhengzhou University First Affiliated Hospital, Zhengzhou, Henan, China.
Clin Appl Thromb Hemost ; 28: 10760296221118489, 2022.
Article en En | MEDLINE | ID: mdl-35945818
The study aimed to evaluate the efficacy and safety of drug coated balloon-only strategy (DCB-only) in the treatment of de novo left main coronary artery (LM) bifurcation lesions. 85 patients were enrolled in this study and classified them into two groups: DCB-only group (n = 36) and DES group (n = 49). The MLD of target vessels was measured before and immediately after percutaneous coronary intervention (PCI) and late luminal loss (LLL) were also calculated. And the occurrence of major adverse cardiovascular events (MACE) was also evaluated. Compared with that before PCI, the MLD of target lesions significantly increased immediately after PCI (P < .05) and no MACE was recorded during the perioperative period both in two groups. The MLD at follow-up was significantly higher than that before both DCB and DES treatment. Compared with the DES group, the MLD of the DCB group was smaller than immediately after PCI in the LM and LAD (P < .05). The LLL of LAD in DCB group was smaller than that in DES group (P < .05). There was no significant difference in the incidence of luminal restenosis at the target lesion between the two groups, and no significant difference in the incidence of MACE (P > .05). The use of DCB-only to treat de novo LM bifurcation lesions is effective and relatively safe, which provides new ideas for the treatment of LM coronary artery bifurcation lesions in the future.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Reestenosis Coronaria / Stents Liberadores de Fármacos / Intervención Coronaria Percutánea Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: Clin Appl Thromb Hemost Asunto de la revista: ANGIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Reestenosis Coronaria / Stents Liberadores de Fármacos / Intervención Coronaria Percutánea Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: Clin Appl Thromb Hemost Asunto de la revista: ANGIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos