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AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling.
Ferrarotto, Renata; Mishra, Vasudha; Herz, Elad; Yaacov, Adar; Solomon, Oz; Rauch, Rami; Mondshine, Adi; Motin, Maria; Leibovich-Rivkin, Tal; Davis, Matti; Kaye, Joel; Weber, Christopher R; Shen, Le; Pearson, Alexander T; Rosenberg, Ari J; Chen, Xiangying; Singh, Alka; Aster, Jon C; Agrawal, Nishant; Izumchenko, Evgeny.
Afiliación
  • Ferrarotto R; Department of Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Mishra V; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL, USA.
  • Herz E; Ayala Pharmaceuticals, Rehovot, Israel.
  • Yaacov A; Ayala Pharmaceuticals, Rehovot, Israel.
  • Solomon O; Ayala Pharmaceuticals, Rehovot, Israel.
  • Rauch R; Ayala Pharmaceuticals, Rehovot, Israel.
  • Mondshine A; Ayala Pharmaceuticals, Rehovot, Israel.
  • Motin M; Ayala Pharmaceuticals, Rehovot, Israel.
  • Leibovich-Rivkin T; Ayala Pharmaceuticals, Rehovot, Israel.
  • Davis M; Ayala Pharmaceuticals, Rehovot, Israel.
  • Kaye J; Ayala Pharmaceuticals, Rehovot, Israel.
  • Weber CR; Department of Pathology, University of Chicago, Chicago, IL, USA.
  • Shen L; Department of Pathology, University of Chicago, Chicago, IL, USA.
  • Pearson AT; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL, USA.
  • Rosenberg AJ; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL, USA.
  • Chen X; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL, USA.
  • Singh A; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL, USA.
  • Aster JC; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Agrawal N; Department of Surgery, Section of Otolaryngology-Head and Neck Surgery, University of Chicago, Chicago, IL, USA.
  • Izumchenko E; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL, USA. izumchen@uchicago.edu.
Cell Death Dis ; 13(8): 678, 2022 08 05.
Article en En | MEDLINE | ID: mdl-35931701
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de las Glándulas Salivales / Carcinoma Adenoide Quístico Límite: Humans Idioma: En Revista: Cell Death Dis Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de las Glándulas Salivales / Carcinoma Adenoide Quístico Límite: Humans Idioma: En Revista: Cell Death Dis Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido