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Effective suppression of myocardial glucose uptake using predesigned low-carbohydrate boxed meals.
Huang, Cheng-Kai; Hou, Po-Nien; Luzhbin, Dmytro; Yang, Chao-Wei; Chang, Yu-Ting; Wu, Jay.
Afiliación
  • Huang CK; Department of Nuclear Medicine, Chung-Kang Branch, Cheng-Ching General Hospital, Taichung, Taiwan.
  • Hou PN; Department of Medical Imaging and Radiology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan.
  • Luzhbin D; Department of Nuclear Medicine, Show Chwan Memorial Hospital, Changhua, Taiwan.
  • Yang CW; Institute of Statistical Science, Academia Sinica, Taipei, Taiwan.
  • Chang YT; Department of Nuclear Medicine, Chung-Kang Branch, Cheng-Ching General Hospital, Taichung, Taiwan.
  • Wu J; Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Linong Street, Taipei, 11221, Taiwan.
J Nucl Cardiol ; 30(2): 484-494, 2023 04.
Article en En | MEDLINE | ID: mdl-35918591
BACKGROUND: Dietary preparation protocols are an effective means to suppress physiological myocardial 18F-fluorodeoxyglucose (FDG) uptake. This study aimed to investigate the efficacy of various carbohydrate-restricted diets using predesigned boxed meals. METHODS: The patients were divided into four groups to undergo different preparatory protocols as follows: a minimum 15-hour fast alone, two meals of high-fat, low-carbohydrate diet (HFLCD), two meals of high-animal-protein, low-carbohydrate diet (HAPLCD), and two meals of high-plant-based-protein, low-carbohydrate diet (HPPLCD). Boxed meals were prepared to meet the required carbohydrate restrictions. Myocardial SUVmax and SUVmean were measured and the suppression rate was analyzed. RESULTS: The average myocardial SUVmax of fast alone, HFLCD, HAPLCD, and HPPLCD were 8.26 ± 5.85, 2.21 ± 1.50, 2.34 ± 1.88, and 4.10 ± 3.61, respectively, and the suppression rates were 36.6%, 93.3%, 93.3%, and 70%, respectively. The effectiveness of HFLCD, HAPLCD, and HPPLCD was all statistically superior to that of a 15-hour fast alone. SUVmax of HFLCD and HAPLCD showed no significant differences (p = 1), whereas HFLCD and HPPLCD had significant differences (p = .046). CONCLUSIONS: Using the predesigned boxed meals based on carbohydrate restriction, HFLCD, HAPLCD, and HPPLCD can be administered to patients with different dietary needs while providing a substantial reduction in physiological myocardial FDG uptake.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Radiofármacos / Fluorodesoxiglucosa F18 Límite: Animals Idioma: En Revista: J Nucl Cardiol Asunto de la revista: CARDIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Radiofármacos / Fluorodesoxiglucosa F18 Límite: Animals Idioma: En Revista: J Nucl Cardiol Asunto de la revista: CARDIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Estados Unidos