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Development of novel ultra-sensitive IL-11 target engagement assays to support mechanistic PK/PD modeling for an anti-IL-11 antibody therapeutic.
Myzithras, Maria; Lin, Siqi; Radden, Legairre; Hess Kenny, Cynthia; Cai, Zheng; MacDonald, Angus; Binetti, Ralph; Marlow, Michael; Fracasso, Paul; Gibson, Glenn; Bartlett, Christina; Hawkins, Julie; Hansel, Steven.
Afiliación
  • Myzithras M; Biotherapeutics Discovery, Research, Ridgefield, CT, USA.
  • Lin S; Biotherapeutics Discovery, Research, Ridgefield, CT, USA.
  • Radden L; Immunology & Respiratory, Research, Ridgefield, CT, USA.
  • Hess Kenny C; Biotherapeutics Discovery, Research, Ridgefield, CT, USA.
  • Cai Z; Biotherapeutics Discovery, Research, Ridgefield, CT, USA.
  • MacDonald A; Immunology & Respiratory, Research, Ridgefield, CT, USA.
  • Binetti R; Immunology & Respiratory, Research, Ridgefield, CT, USA.
  • Marlow M; Biotherapeutics Discovery, Research, Ridgefield, CT, USA.
  • Fracasso P; Cardiometabolic Diseases, Research, Ridgefield, CT, USA.
  • Gibson G; Cardiometabolic Diseases, Research, Ridgefield, CT, USA.
  • Bartlett C; Cardiometabolic Diseases, Research, Ridgefield, CT, USA.
  • Hawkins J; Cardiometabolic Diseases, Research, Ridgefield, CT, USA.
  • Hansel S; Biotherapeutics Discovery, Research, Ridgefield, CT, USA.
MAbs ; 14(1): 2104153, 2022.
Article en En | MEDLINE | ID: mdl-35916739
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina G / Anticuerpos Monoclonales Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina G / Anticuerpos Monoclonales Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos