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Clinical application of mesenchymal stem cell in regenerative medicine: a narrative review.
Margiana, Ria; Markov, Alexander; Zekiy, Angelina O; Hamza, Mohammed Ubaid; Al-Dabbagh, Khalid A; Al-Zubaidi, Sura Hasan; Hameed, Noora M; Ahmad, Irshad; Sivaraman, R; Kzar, Hamzah H; Al-Gazally, Moaed E; Mustafa, Yasser Fakri; Siahmansouri, Homayoon.
Afiliación
  • Margiana R; Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  • Markov A; Master's Programme Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  • Zekiy AO; Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
  • Hamza MU; Tyumen State Medical University, Tyumen, Russian Federation.
  • Al-Dabbagh KA; Tyumen Industrial University, Tyumen, Russian Federation.
  • Al-Zubaidi SH; Department of Prosthetic Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
  • Hameed NM; Medical Technical College, Al-Farahidi University, Baghdad, Iraq.
  • Ahmad I; Department of Dentistry, Al-Hadba University College, Mosul, Iraq.
  • Sivaraman R; Anesthesia Techniques Department, Al-Mustaqbal University College, Babylon, Iraq.
  • Kzar HH; Anesthesia Techniques, Al-Nisour University College, Baghdad, Iraq.
  • Al-Gazally ME; Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
  • Mustafa YF; Department of Mathematics, Dwaraka Doss Goverdhan Doss Vaishnav College, Arumbakkam, University of Madras, Chennai, India.
  • Siahmansouri H; Veterinary Medicine College, Al-Qasim Green University, Al-Qasim, Iraq.
Stem Cell Res Ther ; 13(1): 366, 2022 07 28.
Article en En | MEDLINE | ID: mdl-35902958
The multipotency property of mesenchymal stem cells (MSCs) has attained worldwide consideration because of their immense potential for immunomodulation and their therapeutic function in tissue regeneration. MSCs can migrate to tissue injury areas to contribute to immune modulation, secrete anti-inflammatory cytokines and hide themselves from the immune system. Certainly, various investigations have revealed anti-inflammatory, anti-aging, reconstruction, and wound healing potentials of MSCs in many in vitro and in vivo models. Moreover, current progresses in the field of MSCs biology have facilitated the progress of particular guidelines and quality control approaches, which eventually lead to clinical application of MSCs. In this literature, we provided a brief overview of immunoregulatory characteristics and immunosuppressive activities of MSCs. In addition, we discussed the enhancement, utilization, and therapeutic responses of MSCs in neural, liver, kidney, bone, heart diseases, and wound healing.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Células Madre Mesenquimatosas / Células Madre Mesenquimatosas Tipo de estudio: Guideline / Prognostic_studies Idioma: En Revista: Stem Cell Res Ther Año: 2022 Tipo del documento: Article País de afiliación: Indonesia Pais de publicación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Células Madre Mesenquimatosas / Células Madre Mesenquimatosas Tipo de estudio: Guideline / Prognostic_studies Idioma: En Revista: Stem Cell Res Ther Año: 2022 Tipo del documento: Article País de afiliación: Indonesia Pais de publicación: Reino Unido