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Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity.
Darwish, Salma; Ghazy, Ehab; Heimburg, Tino; Herp, Daniel; Zeyen, Patrik; Salem-Altintas, Rabia; Ridinger, Johannes; Robaa, Dina; Schmidtkunz, Karin; Erdmann, Frank; Schmidt, Matthias; Romier, Christophe; Jung, Manfred; Oehme, Ina; Sippl, Wolfgang.
Afiliación
  • Darwish S; Department of Medicinal Chemistry, Institute of Pharmacy, Martin-Luther University of Halle-Wittenberg, 06120 Halle (Saale), Germany.
  • Ghazy E; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.
  • Heimburg T; Department of Medicinal Chemistry, Institute of Pharmacy, Martin-Luther University of Halle-Wittenberg, 06120 Halle (Saale), Germany.
  • Herp D; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.
  • Zeyen P; Department of Medicinal Chemistry, Institute of Pharmacy, Martin-Luther University of Halle-Wittenberg, 06120 Halle (Saale), Germany.
  • Salem-Altintas R; Institute of Pharmaceutical Sciences, University of Freiburg, 79104 Freiburg, Germany.
  • Ridinger J; Department of Medicinal Chemistry, Institute of Pharmacy, Martin-Luther University of Halle-Wittenberg, 06120 Halle (Saale), Germany.
  • Robaa D; Hopp Children's Cancer Center Heidelberg (KiTZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Schmidtkunz K; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Erdmann F; German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.
  • Schmidt M; Faculty of Medicine, Heidelberg University, 69120 Heidelberg, Germany.
  • Romier C; Hopp Children's Cancer Center Heidelberg (KiTZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Jung M; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Oehme I; German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.
  • Sippl W; Department of Medicinal Chemistry, Institute of Pharmacy, Martin-Luther University of Halle-Wittenberg, 06120 Halle (Saale), Germany.
Int J Mol Sci ; 23(14)2022 Jul 07.
Article en En | MEDLINE | ID: mdl-35886887
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de Histona Desacetilasas / Histona Desacetilasas / Neuroblastoma Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de Histona Desacetilasas / Histona Desacetilasas / Neuroblastoma Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza