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Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice.
Tolani, Bhairavi; Celli, Anna; Yao, Yanmin; Tan, Yong Zi; Fetter, Richard; Liem, Christina R; de Smith, Adam J; Vasanthakumar, Thamiya; Bisignano, Paola; Cotton, Adam D; Seiple, Ian B; Rubinstein, John L; Jost, Marco; Weissman, Jonathan S.
Afiliación
  • Tolani B; Thoracic Oncology Program, Department of Surgery, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA. Bhairavi.Tolani@ucsf.edu.
  • Celli A; Laboratory for Cell Analysis Core Facility, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.
  • Yao Y; Department of Pharmaceutical Chemistry and Cardiovascular Research Institute, University of California, San Francisco, CA, USA.
  • Tan YZ; Molecular Medicine Program, The Hospital for Sick Children, Toronto, ON, Canada.
  • Fetter R; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.
  • Liem CR; Disease Intervention Technology Laboratory, Agency for Science, Technology and Research, Singapore, Singapore.
  • de Smith AJ; Howard Hughes Medical Institute, Department of Biology, Stanford University, Stanford, CA, USA.
  • Vasanthakumar T; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.
  • Bisignano P; Division of Biological Sciences, the Section of Cell and Developmental Biology, University of California San Diego, La Jolla, CA, USA.
  • Cotton AD; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.
  • Seiple IB; Molecular Medicine Program, The Hospital for Sick Children, Toronto, ON, Canada.
  • Rubinstein JL; Department of Biochemistry, The University of Toronto, Toronto, ON, Canada.
  • Jost M; Department of Pharmaceutical Chemistry and Cardiovascular Research Institute, University of California, San Francisco, CA, USA.
  • Weissman JS; Department of Pharmaceutical Chemistry and Cardiovascular Research Institute, University of California, San Francisco, CA, USA.
Nat Biotechnol ; 40(12): 1834-1844, 2022 12.
Article en En | MEDLINE | ID: mdl-35879364
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ATPasas de Translocación de Protón Vacuolares / Neoplasias / Antineoplásicos Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Nat Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ATPasas de Translocación de Protón Vacuolares / Neoplasias / Antineoplásicos Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Nat Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos