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Social frailty increases the risk of all-cause mortality: A longitudinal analysis of the English Longitudinal Study of Ageing.
Ragusa, Francesco Saverio; Veronese, Nicola; Smith, Lee; Koyanagi, Ai; Dominguez, Ligia J; Barbagallo, Mario.
Afiliación
  • Ragusa FS; Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy.
  • Veronese N; Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy. Electronic address: nicola.veronese@unipa.it.
  • Smith L; Centre for Health, Perform and Wellbeing, Anglia Ruskin University, Cambridge, UK.
  • Koyanagi A; Research and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, Barcelona, Spain; ICREA, Pg. Lluis Companys 23, Barcelona, Spain.
  • Dominguez LJ; Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy; Faculty of Medicine and Surgery, University Kore of Enna, Italy.
  • Barbagallo M; Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy.
Exp Gerontol ; 167: 111901, 2022 10 01.
Article en En | MEDLINE | ID: mdl-35870753
OBJECTIVES: Social frailty is a common condition in older people, but its consequences are largely unknown. Therefore, in this longitudinal analysis, we aimed to investigate the association between social frailty and risk of all-cause mortality in a large sample of older people. DESIGN: Longitudinal, cohort. SETTINGS AND PARTICIPANTS: Older people participating to the English Longitudinal Study of Ageing (ELSA). METHODS: Social frailty was defined based on financial difficulty, household status, social activity, and contacts with other people: social frailty was defined as ≥2 points, social pre-frailty (1 point), and robustness (0 points). Survival status during ten years of follow-up was assessed using administrative data. Cox proportional hazard models were used to estimate adjusted hazard ratios (HR) and 95 % confidence intervals (95 % CI) of the association between social frailty status and all-cause mortality. RESULTS: At baseline, compared to social robust participants, social frail subjects reported a significant higher presence of potential risk factors for all-cause mortality. During the ten years of follow-up, after adjusting for 10 potential confounders, social frailty at baseline (vs. robustness) was associated with a significantly higher risk of death (HR = 1.31; 95 % CI: 1.04-1.64; p = 0.02), whilst social pre-frail was not. Among the single factors contributing to social frailty, poverty increased the risk of all-cause mortality by approximately 60 % (HR = 1.60; 95 % CI: 1.33-1.93; p < 0.0001) as well as living alone (HR = 1.46; 95 % CI: 1.10-1.94; p = 0.009). CONCLUSIONS AND IMPLICATIONS: Social frailty was significantly associated with all-cause mortality in a large cohort of older people, highlighting the importance of identifying this phenomenon in older adults to inform targeted intervention efforts.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fragilidad Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Humans Idioma: En Revista: Exp Gerontol Año: 2022 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fragilidad Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Humans Idioma: En Revista: Exp Gerontol Año: 2022 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido