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Interplay between cellular metabolism and DNA viruses.
Zandi, Milad; Shokri, Somayeh; Mahmoudvand, Shahab; Hosseinzadeh Adli, Ahmad; Mohammadi, Ramin; Haddadi, Azita.
Afiliación
  • Zandi M; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
  • Shokri S; Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Mahmoudvand S; Department of Medical Virology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Hosseinzadeh Adli A; Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Mohammadi R; Department of Medical Virology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Haddadi A; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
J Med Virol ; 94(11): 5163-5173, 2022 11.
Article en En | MEDLINE | ID: mdl-35869415
Viruses as intracellular pathogens take over the host metabolism and reprogram to facilitate optimal virus production. DNA viruses can cause alterations in several metabolic pathways, including aerobic glycolysis also known as the Warburg effect, pentose phosphate pathway activation, and amino acid catabolism such as glutaminolysis, nucleotide biosynthesis, lipid metabolism, and amino acid biosynthesis. The available energy for productive infection can be increased in infected cells via modification of different carbon source utilization. This review discusses the metabolic alterations of the DNA viruses that will be the basis for future novel therapeutic approaches.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus / Glucólisis Límite: Humans Idioma: En Revista: J Med Virol Año: 2022 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus / Glucólisis Límite: Humans Idioma: En Revista: J Med Virol Año: 2022 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos