Interplay between cellular metabolism and DNA viruses.
J Med Virol
; 94(11): 5163-5173, 2022 11.
Article
en En
| MEDLINE
| ID: mdl-35869415
Viruses as intracellular pathogens take over the host metabolism and reprogram to facilitate optimal virus production. DNA viruses can cause alterations in several metabolic pathways, including aerobic glycolysis also known as the Warburg effect, pentose phosphate pathway activation, and amino acid catabolism such as glutaminolysis, nucleotide biosynthesis, lipid metabolism, and amino acid biosynthesis. The available energy for productive infection can be increased in infected cells via modification of different carbon source utilization. This review discusses the metabolic alterations of the DNA viruses that will be the basis for future novel therapeutic approaches.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Virus
/
Glucólisis
Límite:
Humans
Idioma:
En
Revista:
J Med Virol
Año:
2022
Tipo del documento:
Article
País de afiliación:
Irán
Pais de publicación:
Estados Unidos