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Effective lens position and pseudophakic refraction prediction error at 10½ years of age in the Infant Aphakia Treatment Study.
VanderVeen, Deborah K; McClatchey, Thaddeus S; McClatchey, Scott K; Nizam, Azhar; Lambert, Scott R.
Afiliación
  • VanderVeen DK; Department of Ophthalmology, Harvard Medical School, Boston, Massachsuetts. Electronic address: deborah.vanderveen@childrens.harvard.edu.
  • McClatchey TS; Department of Ophthalmology, Naval Medical Center, San Diego, California; School of Medicine, California University of Science and Medicine, San Bernardino, California.
  • McClatchey SK; Department of Ophthalmology, Naval Medical Center, San Diego, California; Uniformed Services University of Health Sciences, Bethesda, Maryland.
  • Nizam A; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia.
  • Lambert SR; Department of Ophthalmology, School of Medicine, Stanford University, Palo Alto, California.
J AAPOS ; 26(4): 172.e1-172.e5, 2022 08.
Article en En | MEDLINE | ID: mdl-35868622
BACKGROUND: The refraction prediction error (PE) for infants with intraocular lens (IOL) implantation is large, possibly related to an effective lens position (ELP) that is different than in adult eyes. If these eyes still have nonadult ELPs as they age, this could result in persistently large PE. We aimed to determine whether ELP or biometry at age 10½ years correlated with PE in children enrolled in the Infant Aphakia Treatment Study (IATS). METHODS: We compared the measured refraction of eyes randomized to primary IOL implantation to the "predicted refraction" calculated by the Holladay 1 formula, based on biometry at age 10½ years. Eyes with incomplete data or IOL exchange were excluded. The PE (predicted - measured refraction) and absolute PE were calculated. Measured anterior chamber depth (ACD) was used to assess the effect of ELP on PE. Multiple regression analysis was performed on absolute PE versus axial length, corneal power, rate of refractive growth, refractive error, and best-corrected visual acuity. RESULTS: Forty-three eyes were included. The PE was 0.63 ± 1.68 D; median absolute PE, 0.85 D (IQR, 1.83 D). The median absolute PE was greater when the measured ACD was used to calculate predicted refraction instead of the standard A-constant (1.88 D [IQR, 1.72] D vs 0.85 D [IQR, 1.83], resp. [P = 0.03]). Absolute PE was not significantly correlated with any other parameter. CONCLUSIONS: Variations in ELP did not contribute significantly to PE 10 years after infant cataract surgery.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Afaquia / Errores de Refracción / Lentes Intraoculares Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged80 / Child / Humans / Infant Idioma: En Revista: J AAPOS Asunto de la revista: OFTALMOLOGIA / PEDIATRIA Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Afaquia / Errores de Refracción / Lentes Intraoculares Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged80 / Child / Humans / Infant Idioma: En Revista: J AAPOS Asunto de la revista: OFTALMOLOGIA / PEDIATRIA Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos