Cs2CO3 catalyzed direct aza-Michael addition of azoles to α,ß-unsaturated malonates.
RSC Adv
; 12(30): 19265-19269, 2022 Jun 29.
Article
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| MEDLINE
| ID: mdl-35865588
A highly efficient method for the synthesis of azole derivatives via a direct aza-Michael addition of azoles to α,ß-unsaturated malonates using Cs2CO3 as a catalyst, has been successfully developed. A series of azole derivatives have been obtained in up to 94% yield and the reaction could be amplified to gram scale in excellent yield in the presence of 10 mol% of Cs2CO3.
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01-internacional
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MEDLINE
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En
Revista:
RSC Adv
Año:
2022
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Article
Pais de publicación:
Reino Unido