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A fabric-based multifunctional sensor for the early detection of skin decubitus ulcers.
Kim, Seung-Rok; Lee, Soyeon; Kim, Jihee; Kim, Eunbin; Kil, Hye-Jun; Yoo, Ju-Hyun; Oh, Je-Heon; Jeon, Jiwan; Lee, Ey-In; Jeon, Jun-Woo; Jeon, Kun-Hoo; Lee, Ju Hee; Park, Jin-Woo.
Afiliación
  • Kim SR; Department of Materials Science and Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
  • Lee S; Department of Materials Science and Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea; Asen Company, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
  • Kim J; Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, College of Medicine, Yonsei University, Seoul, 03722, South Korea; Scar Laser and Plastic Surgery Center, Yonsei Cancer Hospital, College of Medicine, Yonsei University, Seoul, 03722, South Korea; Department of Derm
  • Kim E; Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, College of Medicine, Yonsei University, Seoul, 03722, South Korea; Scar Laser and Plastic Surgery Center, Yonsei Cancer Hospital, College of Medicine, Yonsei University, Seoul, 03722, South Korea.
  • Kil HJ; Department of Materials Science and Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
  • Yoo JH; Department of Materials Science and Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
  • Oh JH; Department of Materials Science and Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
  • Jeon J; Department of Materials Science and Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
  • Lee EI; Department of Materials Science and Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
  • Jeon JW; Department of Materials Science and Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
  • Jeon KH; Department of Materials Science and Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
  • Lee JH; Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, College of Medicine, Yonsei University, Seoul, 03722, South Korea; Scar Laser and Plastic Surgery Center, Yonsei Cancer Hospital, College of Medicine, Yonsei University, Seoul, 03722, South Korea. Electronic address
  • Park JW; Department of Materials Science and Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea; Asen Company, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea. Electronic address: jwpark09@yonsei.ac.kr.
Biosens Bioelectron ; 215: 114555, 2022 Nov 01.
Article en En | MEDLINE | ID: mdl-35863135
Monitoring biosignals at the skin interface is necessary to suppress the potential for decubitus ulcers in immobile patients confined to bed. We develop conformally contacted, disposable, and breathable fabric-based electronic devices to detect skin impedance, applied pressure, and temperature, simultaneously. Based on the experimental evaluation of the multifunctional sensors, a combination of robust AgNW electrodes, soft ionogel capacitive pressure sensor, and resistive temperature sensor on fabric provides alarmed the initiation of early-stage decubitus ulcers without signal distortion under the external stimulus. For clinical verification, an animal model is established with a pair of magnets to mimic a human decubitus ulcers model in murine in vivo. The evidence of pressure-induced ischemic injury is confirmed with the naked eye and histological and molecular biomarker analyses. Our multifunctional integrated sensor detects the critical time for early-stage decubitus ulcer, establishing a robust correlation with the biophysical parameters of skin ischemia and integrity, including temperature and impedance.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Técnicas Biosensibles / Úlcera por Presión Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Biosens Bioelectron Asunto de la revista: BIOTECNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Corea del Sur Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Técnicas Biosensibles / Úlcera por Presión Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Biosens Bioelectron Asunto de la revista: BIOTECNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Corea del Sur Pais de publicación: Reino Unido