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Genomic and epigenomic BRCA alterations predict adaptive resistance and response to platinum-based therapy in patients with triple-negative breast and ovarian carcinomas.
Menghi, Francesca; Banda, Kalyan; Kumar, Pooja; Straub, Robert; Dobrolecki, Lacey; Rodriguez, Isabel V; Yost, Susan E; Chandok, Harshpreet; Radke, Marc R; Somlo, George; Yuan, Yuan; Lewis, Michael T; Swisher, Elizabeth M; Liu, Edison T.
Afiliación
  • Menghi F; Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA.
  • Banda K; Division of Medical Oncology, UW Medical Center, Seattle, WA 98195, USA.
  • Kumar P; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Straub R; Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA.
  • Dobrolecki L; Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA.
  • Rodriguez IV; Lester and Sue Smith Breast Center, Houston, TX 77030, USA.
  • Yost SE; Department of Obstetrics and Gynecology, UW Medical Center, Seattle, WA 98195, USA.
  • Chandok H; Division of Medical Oncology and Therapeutic Research, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.
  • Radke MR; Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA.
  • Somlo G; Department of Obstetrics and Gynecology, UW Medical Center, Seattle, WA 98195, USA.
  • Yuan Y; Division of Medical Oncology and Therapeutic Research, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.
  • Lewis MT; Division of Medical Oncology and Therapeutic Research, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.
  • Swisher EM; Departments of Molecular and Cellular Biology and Radiology, Lester and Sue Smith Breast Center, Dan L Duncan Comprehensive Cancer Center, Houston, TX 77030, USA.
  • Liu ET; Department of Obstetrics and Gynecology, UW Medical Center, Seattle, WA 98195, USA.
Sci Transl Med ; 14(652): eabn1926, 2022 07 06.
Article en En | MEDLINE | ID: mdl-35857626
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Carcinoma / Neoplasias de la Mama Triple Negativas Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Carcinoma / Neoplasias de la Mama Triple Negativas Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos